首页|Role of cyclooxygenase-2 in lipid metabolism in hepatic stellate cells

Role of cyclooxygenase-2 in lipid metabolism in hepatic stellate cells

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Hepatic stellate cells (HSCs) are a kind of adipocytes.In HSCs lipids mainly exist in the form of lipid droplets.They are abundantly found in the cytoplasm and their main constituents are triglycerides.Lipid metabolism in HSCs is closely related to its biological activity,however the mechanism of lipid droplets disappearance after HSC activation is not clearly established yet.Recent research shows that,cyclooxygenase-2 plays an important regulatory role in the lipid metabolism of HSCs.This paper seeks to review the subject based on studies that have been conducted so far to understand the role of cyclooxygenase-2 in the metabolism of lipids in HSCs.

Hepatic stellate cellsLipid metabolismCyclooxygenase-2

JING Xinyan、YANG Xuefeng、OU Yangyan、QING Kai

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1Department of Gastroenterology, the Affiliated Nanhua Hospital of the University of South China, Hengyang 421000, Hunan, China

Department of Nephrology, Ruijin Hospital, the Shanghai Jiaotong University, Shanghai 200025, China

Department of Hematology, Ruijin Hospital, the Shanghai Jiaotong University, Shanghai 200025, China

National Natural Science Foundation of China

81373465

2013

中国人民解放军军医大学学报(英文版)
第一(现南方医科大学),二,三,四军医大学

中国人民解放军军医大学学报(英文版)

影响因子：0.245
ISSN：1000-1948
年,卷(期)：2013.28(6)
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