Study on the effect of compound probiotics on improving immunosuppression
A The paper was conducted on Lactobacillus acidophilus LA-06,Bifidobacterium animalis subsp.Lactis XLTG11,Lactobacillus casei Glory LC18,and Lactobacillus rhamnosus Glory LG12 in a ratio of 40∶20∶20∶9,using oligofructose and maltodextrin as the matrix,to prepare a composite probiotic powder to improve the immunosuppressive effect in mice.Immunosuppression was studied by injection of cyclophosphamide for modeling with three gradients(1 ×106,1×107,1 ×108 CFU/pc),and body weight,immune organ index,cellular immunity,humoral immunity,and nonspecific immunity were measured.The results showed that body weight gain,thymus index,spleen index,foot-plantar thickness,antibody accumulation,NK cell activity,and phagocytosis index of mice in the compound probiotic group were increased by 62％,65％,13％,30％,26％,40％,and 25％,respectively,compared with the model group.It was inferred that the probiotic complex had a promotive effect on the immune function of mice.
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维普
