摘要
文章探究马乳、驴乳、驼乳对小鼠生长、免疫和抗氧化能力的影响.以4周龄小鼠32只为研究对象,随机分为对照组、马乳组、驴乳组和驼乳组,每天根据体质量分别灌胃10 g/kg体质量蒸馏水、马乳、驴乳和驼乳,在第29天处死小鼠后采集肝脏组织,测定小鼠的免疫和抗氧化指标.结果表明,与对照组相比,马乳组和驼乳组15～21 d和22～28 d时平均日采食量极显著降低,马乳组脾脏指数、白介素1β、超氧化物歧化酶活性显著升高,白细胞介素-6、丙二醛浓度显著降低;驴乳组脾脏指数、蛋白质浓度、超氧化物歧化酶活性显著升高,白细胞介素-6、丙二醛浓度显著降低;驼乳组脾脏指数、白介素1β、蛋白质浓度、超氧化物歧化酶活性显著升高,丙二醛浓度显著降低.灌灌胃马乳和驼乳能够降低小鼠日采食量,灌胃马乳、驴乳、驼乳能够改善小鼠的免疫和抗氧化能力.
Abstract
This study aimed to investigate the effects of mare's milk,donkey's milk,and camel's milk on the growth,immunity,and antioxidant performance of mice.Thirty-two four-week-old mice were randomly divided into control group,mare milk group,donkey milk group,and camel milk group.Each group was orally administered 10 g/kg(body weight)of distilled water,mare milk,donkey milk,or camel milk daily ac-cording to body weight.On the 29th day,the mice were sacrificed,and liver tissue was collected to measure the immune and antioxidant indica-tors.The results show that compared to the control group,the average daily intake of the mare milk group and the camel milk group decreased sig-nificantly during 15～21 d and 22～28 d.The spleen index,interleukin-1β,and superoxide dismutase activity in the mare milk group increased sig-nificantly,while interleukin-6 and malondialdehyde concentration decreased significantly.In the donkey milk group,the spleen index,protein concentration,and superoxide dismutase activity increased significantly,while interleukin-6 and malondialdehyde concentration decreased signifi-cantly.In the camel milk group,the spleen index,interleukin-1β,protein concentration,and superoxide dismutase activity increased significantly,while malondialdehyde concentration decreased significantly.Gastric infusion of mare milk and camel milk can reduce the daily intake of mice.Feeding mare milk,donkey milk,and camel milk can improve the immune and antioxidant functions of mice.
基金项目
自治区重大科技专项(2022A02013-1)
自治区创新环境(人才、基地)建设专项(PT2311)
中央引导地方科技发展专项资金项目(ZYYD2023C02)
维普
万方数据