首页|新疆生产建设兵团人间布鲁氏菌病流行特征分析及发病趋势预测

新疆生产建设兵团人间布鲁氏菌病流行特征分析及发病趋势预测

Analysis of epidemic status and prediction of incidence trends of human brucellosis in Xinjiang Production and Construction Corps

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目的 分析新疆生产建设兵团2010-2022年布病流行特征,建立Holt-Winters乘法模型(Holt-Winters Smoot-hing,HWS)并预测后期布病发病趋势,为制定布病防治措施提供参考依据.方法 收集"中国疾病预防控制信息系统"的传染病报告信息管理系统中的兵团2010-2022年布病发病数据,采用描述性流行病学方法分析兵团2010-2022年布病流行特征;运用python 3.7软件建立Holt-Winters模型并预测兵团2022-2024年布病月发病数.结果 兵团2010-2022年共报告布病病例6 278例,年均报告发病率为16.68/10万,整体呈现上升趋势(趋势x2=44.874,P<0.001).发病高峰主要集中在4-7 月,占比 52.37%(3 288/6 278);其中,5 月病例最多 1 935 例(14.89%).男女性别比为 2.71:1(x2=29.966,P<0.01),发病年龄主要集中于40~60岁年龄组,共3 807例(60.64%),职业主要以农牧民为主(农牧民组和非农牧民组x2=97.209,P<0.001).兵团报告病例数最多的地区为第八师1 051例(16.76%);其次为第六师911例(14.53%)和第三师853例(13.60%).Holt-Winters乘法模型预测2022-2024年报告发病数分别为675例、644例和679例,预测模型的R2=0.78,拟合效果较好.结论 近年来,兵团布病发病人数整体仍处于上升阶段,兵团各师应继续加强对于布病的管控.
The purpose of this study was to analyze the epidemic characteristics of brucellosis in Xinjiang Production and Construction Corps from 2010 to 2022;establish a Holt-Winters Smoothing(HWS)model and predict the incidence trends of brucellosis in the later period;and provide a reference for preventive measures.Brucellosis data from 2010 to 2022 were collect-ed from the infectious disease reporting information management system of the China Disease Prevention and Control Informa-tion System.Descriptive epidemiological methods were used to analyze the epidemic characteristics of brucellosis from 2010 to 2022.The Holt-Winters model was established in Python 3.7 software and used to predict the number of brucellosis cases in 2022-2024.A total of 6 278 cases of brucellosis were reported from 2010 to 2022.The annual reported incidence was 16.68/100 000,and showed an increasing trend(trend X2=44.874,P<0.001).The incidence peak was primarily from April to July,accounting for 52.37%(3 288/6 278).The highest number of cases,in May,was 1 935(14.89%).The sex ratio was 2.71:1(X2=29.966,P<0.01).The primary age group affected by the disease was 40-60 years,with 3 807 cases(60.64%),and the main occupations were farmers and herders(farmer and herder group X2=97.209,P<0.001).The highest number of cases was 1051(16.76%)in the 8th division,and was followed by the 6th division,with 911 cases(14.53%),and the 3rd division,with 853 cases(13.60%).The Holt-Winters multiplication model pre-dicted that 675,644 and 679 cases would be reported in 2022,2023 and 2024,respectively.The R2 of the predictive model was 0.78,thus indicating a good fitting effect.In conclusion,in recent years,the number of cases of brucellosis has increased,and all di-visions of the Corps should continue to strengthen brucellosis control measures.

brucellosisXinjiang Production and Construction Corpsepidemiological characteristicsdisease prediction

范奔、马晓玲、杨柳根、赵倩、王童敏、李凡卡

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石河子大学医学院预防医学系,石河子 832000

新疆生产建设兵团疾病预防控制中心,乌鲁木齐 830002

布鲁氏菌病 新疆生产建设兵团 流行特征 发病预测

新疆生产建设兵团疾病预防控制中心自主课题

BTCDCKY202203

2024

中国人兽共患病学报
中国微生物学会

中国人兽共患病学报

CSTPCD北大核心
影响因子:0.814
ISSN:1002-2694
年,卷(期):2024.40(3)
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