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蜱传脑炎概况及其防治研究进展

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蜱传脑炎病毒(Tick-borne encephalitis virus,TBEV)是引起中枢神经系统疾病——蜱传脑炎(Tick-borne en-cephalitis,TBE)的病原体,可在人与动物中引起致死性脑炎并伴有长期的后遗症,严重影响人类健康与公共卫生安全.近年来随着气候变化以及人类对自然资源的开发,蜱传脑炎发病率不断升高,但目前尚无有效的治疗药物,靶向抗病毒药物的研发是治疗病毒感染的主要方向之一.蜱传脑炎的预防主要集中在减少传播媒介蜱的叮咬上.本文对蜱传脑炎病毒的病原学特征、临床特征、检测诊断方法以及防治措施进行综述,以期为相关研究提供参考.
Overview of tick-borne encephalitis and research progress in prevention and control
Tick-borne encephalitis virus(TBEV)is the causative agent of the neurological disease tick-borne encephalitis(TBE),which can cause lethal encephalitis in human and animals with long-term sequelae,thus posing a great threat to life and public health.With the development of natural resources and climate change,the incidence of tick-borne encephalitis has continued to increase.However,there are no effective drugs for treatment of TBEV.Targeted anti-TBEV inhibitors have po-tential for treatment of TBEV infection.Prevention of TBEV infection has mainly focused on avoiding tick bites.In this paper,the pathogenic characteristics,clinical features,detection,diagnosis,prevention,and treatment of TBEV infection are re-viewed,as references for related research.

tick-borne encephalitis virus(TBEV)pathogenesisprevention and controltick

张芳、王小恒

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西北民族大学医学部,兰州 730030

蜱传脑炎病毒 病原学 防治

中央高校基本科研业务费专项西北民族大学引进人才项目

31920230191xbmuyjr202234

2024

中国人兽共患病学报
中国微生物学会

中国人兽共患病学报

CSTPCD北大核心
影响因子:0.814
ISSN:1002-2694
年,卷(期):2024.40(4)
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