首页|2017-2022年武汉地区儿童食源性疾病监测中沙门氏菌感染情况和耐药性分析

2017-2022年武汉地区儿童食源性疾病监测中沙门氏菌感染情况和耐药性分析

扫码查看
目的 分析2017-2022年武汉地区食源性疾病主动监测中儿童沙门氏菌感染率、血清型分布及耐药率,为儿童群体的食源性疾病防控工作提供依据.方法 收集2017-2022年武汉地区儿童食源性疾病病例和病例粪便标本病原学监测结果,应用SPSS 22.0进行统计分析.结果 共监测病例1 180例,检出281株沙门氏菌,平均检出率为23.81%.沙门氏菌包含27种血清型,以鼠伤寒沙门菌138株(49.11%)和肠炎沙门菌37株(13.17%)为主.沙门氏菌阳性病例中,男女病例比为1.58∶1,检出率最高的年龄组为7~18岁组(34.48%).可疑暴露食品中乳与乳制品、水果类及其制品、粮食类及其制品的沙门氏菌检出率较高.沙门氏菌在第3季度检出率最高(44.64%),不同季节沙门氏菌样本阳性率差异有统计学意义(x2=178.483,P<0.05).沙门氏菌感染患儿主要临床表现为发热(87.19%)和腹泻(96.44%),腹泻以水样便为主,占51.96%.沙门氏菌对14种抗生素均有不同程度的耐药(1.08%~75.99%),耐药率居前3位的抗生素分别是氨苄西林(75.99%)、四环素(68.10%)和头孢唑啉(50.18%).结论 武汉地区儿童食源性疾病沙门氏菌检出存在明显的季节性,各类可疑暴露食品中均有检出,血清型构成呈多态性,沙门氏菌耐药率较高,要继续加强食源性疾病主动监测和沙门氏菌耐药监测.
Salmonella infection and drug resistance in foodborne disease surveillance among children in Wuhan from 2017 to 2022
This study was aimed at analyzing the Salmonella infection rate,serotype distribution,and drug resistance rate among children with foodborne diseases in Wuhan,to provide evidence for the prevention and control of foodborne diseases in children.We collected pediatric cases of foodborne diseases and fecal specimens in Wuhan from 2017 to 2022,and conducted statistical analysis in SPSS 22.0.A total of 1 180 cases of foodborne diseases in children were monitored,and 281 strains of Salmonella were detected.Salmonella was distributed across 27 serotypes,primarily Salmonella enteritidis(138 strains,ac-counting for 49.11%)and Salmonella typhimurium(37 strains,accounting for 13.17%).The Salmonella-positive cases in-cluded more boys than girls(1.58∶1 ratio),and the age group with the highest detection rate was 7-18 years(34.48%).The proportion of positive patients gradually decreased,and the detection rate gradually increased,with increasing age.Milk and dairy products,fruits and fruit products,and grain and grain products were the main suspected food exposures with high Sal-monella detection rates.The Salmonella detection rate was highest in the third quarter(44.64%),and significant differences were observed in the positivity rates of Salmonella samples across seasons(x2=178.483,P<0.05).The main clinical mani-festations of children with Salmonella infection were fever(87.19%)and diarrhea(96.44%),primarily watery stool(51.96%).Salmonella showed different degrees of resistance to 14 antibiotics(1.08%-75.99%),primarily ampicillin(75.99%),tetracycline(68.10%),and cefazolin(50.18%).A significant seasonal pattern was observed in the detection of Sal-monella in foodborne diseases among children in Wuhan,and in various suspected food exposures.The serotype composition was polymorphic,and the Salmonella resistance rate was relatively high.Therefore,active monitoring of foodborne diseases and Salmonella resistance surveillance must continue to be strengthened.

foodborne diseasesSalmonellachildrendrug resistance

聂丽、邓颖、罗万军、唐锋

展开 >

华中科技大学同济医学院附属武汉儿童医院(武汉市妇幼保健院),武汉 430014

食源性疾病 沙门氏菌 儿童 耐药性

国家自然科学基金面上项目武汉市卫生健康委员会面上项目武汉市卫生健康青年人才研修项目联合资助

82072351WX20C10

2024

中国人兽共患病学报
中国微生物学会

中国人兽共患病学报

CSTPCD北大核心
影响因子:0.814
ISSN:1002-2694
年,卷(期):2024.40(8)
  • 12