首页|布鲁氏菌主要外膜蛋白研究进展

布鲁氏菌主要外膜蛋白研究进展

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布鲁氏菌病是一种世界范围流行的细菌性人兽共患传染病,由布鲁氏菌属细菌引起,给畜牧业生产和公共卫生安全带来了极大的威胁.外膜蛋白是布鲁氏菌主要的免疫和保护性抗原,与布鲁氏菌的毒力、免疫调节和胞内寄生等特性密切相关.本文对布鲁氏菌主要外膜蛋白的研究进展予以综述,从而促进对布鲁氏菌抗原特性的理解,为布鲁氏菌新型诊断方法的建立和疫苗设计提供参考.
Research progress in Brucella main outer membrane proteins
Brucellosis,a worldwide epidemic bacterial zoonotic infectious disease caused by bacteria of the genus Brucella,jeopardizes livestock production and poses a major threat to public health safety.Among the various components of Brucella,the outer membrane proteins play crucial roles as the primary immune and protective antigens.These proteins are closely asso-ciated with Brucella's virulence,regulation of the immune response,and ability to survive and multiply within host cells.This article summarizes recent research progress in the primary outer membrane proteins of Brucella,and offers a synthesized view of the current knowledge landscape.Understanding the antigenic characteristics of Brucella outer membrane proteins may sub-stantially contribute to the establishment of new diagnostic methods and the design of new vaccines,thus potentially leading to more effective prevention strategies against brucellosis.The review provides a reference for future studies and may aid in brucel-losis control efforts.

Brucellaouter membrane proteinsantigenic properties

辛雪强、佟彤、王玉金、盛宇杰、徐正中、陈祥

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扬州大学江苏省人兽共患病学重点实验室/江苏省动物重要疫病与人兽共患病防控协同创新中心,扬州 225009

扬州大学农业农村部农产品质量安全生物性危害因子(动物源)控制重点实验室,扬州 225009

布鲁氏菌 外膜蛋白 抗原特性

国家重点研发计划江苏高等学校大学生创新创业训练计划项目江苏高校优势学科建设工程项目(PAPD)

2021YFD1800403202311117042Z

2024

中国人兽共患病学报
中国微生物学会

中国人兽共患病学报

CSTPCD北大核心
影响因子:0.814
ISSN:1002-2694
年,卷(期):2024.40(9)
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