Analysis of clinical characteristics and risk factors of patients with sever melioidosis
This study was aimed at investigating the clinical features and risk factors for patients with severe melioidosis,to increase early diagnosis rates and decrease mortality.The clinical data for 80 patients with melioidosis treated in hospital be-tween January 2018 and August 2023 were collected and analyzed with a logistic regression model.Among these patients,32 were diagnosed with severe melioidosis,and presented with symptoms such as chest tightness,chest pain,and shock in early stages.Common abnormalities found in severe melioidosis included high infectious indicators and liver dysfunction.Diabetes mellitus(OR=6.038,95％CI:1.070-34.083),chest tightness or chest pain(OR=20.375,95％CI:2.447-169.636),shock(OR=1.756,95％CI:1.756-227.291),high aspartic transaminase(OR=1.001,95％CI:1.001-1.042),and high direct bilirubin(OR=1.013,95％CI:1.013-1.214)were identified as risk factors for severe melioidosis.In conclusion,chest tightness,chest pain,shock,high infectious indicators,and liver dysfunction were significant clinical features of severe me-lioidosis.Risk factors such as diabetes mellitus,chest tightness or pain,shock,high aspartic transaminase,and high direct bil-irubin may aid in the early diagnosis of severe melioidosis.
万方数据
维普
