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中药复方治疗犊牛牛病毒性腹泻的疗效研究

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[目的]探究中药复方对犊牛牛病毒性腹泻的治疗效果.[方法]本试验于山东省聊城市阳谷县某私人养殖场挑选52 头体重相近的牛病毒性腹泻患病犊牛,随机分为4组,每组13 头,即对照组、中药复方低剂量组、中药复方中剂量组和中药复方高剂量组,分别口服0 g/次、100 g/次、150 g/次和200 g/次中药复方,每日给药2 次,连续给药5 d.[结果]中药复方高剂量组患病犊牛的有效率和治愈率分别为92.31%和69.23%.与对照组相比,中药复方低、中和高剂量组患病犊牛血清中的白细胞介素1β、白细胞介素2和肿瘤坏死因子α含量显著升高(P<0.05),白细胞介素4含量显著降低(P<0.05).与对照组相比,中药复方中、高剂量组患病犊牛血清中的免疫球蛋白G显著升高(P<0.05),中药复方低、中和高剂量组患病犊牛血清中的免疫球蛋白A和CD4含量显著升高(P<0.05).[结论]中药复方对犊牛牛病毒性腹泻有良好治疗效果,改善炎性因子水平,提高患牛免疫能力,其中给药200 g/次的中药复方组效果较好.
Study on the Curative Effect of Traditional Chinese Medicine Compound on Calf Viral Diarrhea
[Objective]To explore the therapeutic effect of traditional Chinese medicine compound on calf viral diarrhea.[Method]In this experiment,52 calves with bovine viral diarrhea were selected from a private farm in yanggu county,Liaocheng City,Shandong Province,and randomly divided into 4 groups,with 13 calves in each group,namely,the control group,the low-dose group,the middle-dose group and the high-dose group.The traditional Chinese medicine compound was given orally at 0,100,150 and 200 g/time,respectively,twice a day for 5 days.[Result]The effective rate and cure rate of sick calves in the high-dose group of traditional Chinese medicine compound were 92.31%and 69.23%respectively.Compared with the control group,the contents of IL-1β,IL-2 and TNF-α in the serum of sick calves in low,medium and high dose groups of Chinese herbal compound increased significantly(P<0.05),while the content of IL-4 decreased significantly(P<0.05).Compared with the control group,the serum immunoglobulin G in the middle and high doses of Chinese herbal compound increased significantly(P<0.05),and the serum immunoglobulin A and CD4 contents in the low,middle and high doses of Chinese herbal compound increased significantly(P<0.05).[Conclusion]Traditional Chinese medicine compound has a good therapeutic effect on calf viral diarrhea,improving the level of inflammatory factors and improving the immune ability of infected cows,among which the effect of traditional Chinese medicine compound group with 200 g/time is better.

traditional Chinese medicine compoundBovine viral diarrheatherapeutic effectinflammatoryimmune

马立勇

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山东省聊城市阳谷县畜牧兽医事业发展中心,山东聊城 252300

中药复方 牛病毒性腹泻 疗效 炎性 免疫

2024

中国乳业
中国奶业协会 中国农业科学院信息研究所

中国乳业

影响因子:0.152
ISSN:1671-4393
年,卷(期):2024.(3)
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