首页|短链氯化石蜡在海洋环境中的分布及生态毒理效应

短链氯化石蜡在海洋环境中的分布及生态毒理效应

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  • 国家科技期刊平台
  • NETL
  • NSTL
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短链氯化石蜡(Short-chain chlorinated paraffin,SCCPs)受工业活动及季风气候影响,在中国海洋环境中的分布总体上呈现沿岸大于深海.由于其具有较高的亲脂性和疏水性,极易在生物体内聚集,并可通过食物网传递产生生物放大效应.此外,大量的毒理研究表明,SCCPs主要通过代谢紊乱、氧化应激、内分泌失调及与生物大分子结合等机制,对生物体产生潜在的发育毒性、肝毒性、内分泌紊乱以及神经毒性等.在未来还需借助组学等技术分析完善SC-CPs的潜在毒性,通过更多的体外实验分析其在人体的暴露风险.[中国渔业质量与标准,2024,14(3):33-42]
Distribution and toxicological effects of short-chained chlorinated paraffins in the marine environment
The distribution of short-chained chlorinated paraffins(SCCPs)in China's marine environment is predom-inantly coastal rather than deep-sea,influenced by industrial activities and the monsoon climate.Due to their high lipophilicity,and hydrophobicity,they are highly susceptible to aggregate in organisms and can undergo trophic am-plification through food web transfer.In addition,a large number of toxicological studies have shown that SCCPs have potential developmental toxicity,hepatotoxicity,endocrine disruption,and neurotoxicity on organisms through meta-bolic disorders,oxidative stress,endocrine disruption and binding to biomolecules.In the future,it is necessary to analyze the potential toxicity of SCCPs with the help of histology and other techniques and to assess the risk of human exposure through increasing in vitro experiments.[Chinese Fishery Quality and Standards,2024,14(3):33-42]

bioaccumulationbiomagnificationtoxicity mechanismsfood webmarine environment

宋敏、韩典峰、丁玉竹、刘小静、刘永春、薛敬林、王明磊、李佳蔚、王景、章寸心、徐英江

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山东省海洋资源与环境研究院,山东 烟台 264006

上海海洋大学食品学院,上海 201306

生物蓄积 生物放大 毒性机制 食物网 海洋环境

山东省自然科学基金面上项目山东省现代农业产业技术体系建设项目山东省现代农业产业技术体系建设项目烟台市科技创新发展计划烟台市科技创新发展计划

ZR2023MD121SDAIT-26-05SDAIT-14-082023YD0892023YD090

2024

10.3969/j.issn.2095-1833.2024.03.005

中国渔业质量与标准
中国水产科学研究院

中国渔业质量与标准

影响因子：0.707
ISSN：2095-1833
年,卷(期)：2024.14(3)
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