New psychoactive substances(NPS),as the third generation of drugs after traditional drugs and synthetic drugs,are being abused globally,and have become a prominent issue of priority concern for countries around the world.Novel synthetic opioids are one of the most potentially harmful substances and have been abused increasingly,posing a serious threat to human health and public safety.As one class of novel synthetic opioids,the problem of manufacturing,smuggling and abuse of Nitazenes are becoming more and more seriously all over the world.In this paper,the basic structure,abuse and control,pharmacological and toxicological properties,metabolism and detection methods of Nitazenes were reviewed.Moreover,the development of detection technology of Nitazenes were briefly prospected,in order to provide reference for further study of Nitazenes.
关键词
新精神活性物质/尼秦类物质/药理和毒理学/代谢/检验方法
Key words
new psychoactive substance(NPS)/Nitazene/pharmacology and toxicology/metabolism/testing method