P300 in Psychiatric Impairment Assessment during Psychiatric Disorders Caused by Traumatic Subarachnoid Hemorrhage
Objective To explore the role of P300 in impairment appraisal during psychiatric disorders caused by traumatic subarachnoid hemorrhage(TSAH).Methods Sixteen patients who met the criteria for organic mental disorders(only caused by TSAH)according to the 10th version of the International Classification of Diseases(ICD-10)were included,along with seventeen healthy controls matched for gender,age,and educational level.P300 detection was conducted on the participants using a visual Oddball paradigm;meanwhile,assessments were made using scales such as the activity of daily living(ADL)scale and the social disability screening schedule(SDSS).Results The P300 amplitudes at points Fz,Cz,CPz,and Pz in the TSAH group were significantly lower than those in the healthy control group(P<0.05).The P300 latencies at points Cz,CPz,and Pz in the TSAH group were prolonged compared to the healthy control group(P<0.05).There was a negative correlation between the amplitudes at points Fz,Cz,CPz,and Pz with the ADL scale and SDSS scores in the TSAH group(P<0.05).Additionally,there was a positive correlation between the P300 latencies at points Cz,CPz,and Pz with ADL scale scores and the P300 latency at point Pz with the SDSS scores in the TSAH group(P<0.05).Conclusion The amplitude of P300 can reflect the severity of mental disorders caused by TSAH,with lower P300 amplitudes indicating more severe conditions.P300 amplitude can serve as a reference indicator for psychiatric impairment appraisal during psychiatric disorders caused by TSAH.
万方数据
维普
