首页|柴胡疏肝汤联合团体认知行为治疗对脑卒中后抑郁患者HAMD和NIHSS评分的影响

柴胡疏肝汤联合团体认知行为治疗对脑卒中后抑郁患者HAMD和NIHSS评分的影响

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目的 探讨团体认知行为治疗结合柴胡疏肝汤对脑卒中后抑郁的疗效及患者神经功能缺损的影响.方法 天津中医药大学第一附属医院脑病康复科收治的80例PSD患者随机分为对照组和观察组,每组40例.所有的患者给予常规药物治疗和康复功能训练,加服氟哌噻吨美利曲新.观察组在对照组治疗的基础上加柴胡疏肝汤治疗以及团体认知行为治疗.2组患者分别与治疗前24h及治疗8周后进行汉密顿抑郁量表、神经功能缺损程度量表和巴塞尔指数评定.结果 治疗8周后,观察组总有效率为95%(38/40),对照组为75%(30/40),差异有统计学意义(P<0.05).观察组的HAMD、NIHSS和BI评分改善均显著优于对照组,差异有统计学意义(P<0.05).结论 柴胡疏肝汤联合团体认知行为治疗治疗PSD患者具有增效作用,可显著改善患者抑郁症状和神经功能缺损情况,并可改善患者生活质量.
Chaihu Shugan decoction combined with Group cognitive behavioral therapy on effect of HAMD and NIHSS in patients with depression after stroke
Objective To investigate the Chaihu Shugan decoction combined with Group cognitive behavioral therapy on curative effect and neurologic impairment in patients with depression after stroke. Methods 80 PSD patients were randomly divided into our hospital encephalopathy rehabilitation were selected as control group and observation group, 40 cases in each group. The routine drug treatment and rehabilitation training for all patients with Deanxit tablet. The observation group added ChaiHuShuGan Decoction and group cognitive behavioral therapy in the control group based on the treatment. Two groups of patients with 24h before treatment and after 8 weeks of treatment, the Hamilton Depression Scale, the degree of neural function defect scale and evaluation index of Basel. Results After 8 weeks treatment, the total effective rate of the observation group was 95% (38 / 40), and the control group was 75% (40/30), the difference was statistically significant (P<0.05). The improvement of HAMD, NIHSS and BI scores in the observation group were significantly better than those in the control group, the difference was statistically significant (P<0.05). Conclusion ChaiHuShuGan Decoction has synergistic effect with Group cognitive behavioral therapy in the treatment of PSD can significantly improve the symptoms of depression and neurologic impairment, and can improve the quality of life of patients.

group cognitive behavioral therapyChaihu Shugan decoctionpost stroke depression

刘彬

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天津中医药大学第一附属医院 脑病康复科,天津 300193

团体认知行为治疗 柴胡疏肝汤 脑卒中后抑郁

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(1)
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