首页|腹腔镜卵巢剥脱术联合孕三烯酮治疗卵巢囊肿的临床疗效及对FSH、LH和E2的影响

腹腔镜卵巢剥脱术联合孕三烯酮治疗卵巢囊肿的临床疗效及对FSH、LH和E2的影响

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目的 探讨腹腔镜卵巢剥脱术联合孕三烯酮治疗卵巢囊肿的临床疗效及对FSH、LH和E2的影响.为临床诊断治疗提供参考依据.方法 选择2014年6月~2016年6月路桥区第三人民医院及台州市中心医院收治的60例卵巢囊肿患者,采用随机数字表法将他们随机分为对照组和治疗组,每组各30例.治疗组腹腔镜卵巢剥脱术口服孕三烯酮治疗,2组的患者均治疗6个月作为一个疗程.采用放射免疫法对FSH、LH和E2进行检测,窦状卵泡数量在阴式超声下进行.结果 治疗组治疗后总有效率(80%)显著高于对照组有效率(40%),差异有统计学意义(P<0.05);治疗组与对照组患者术后口服孕三烯酮后FSH、LH、E2水平及窦状卵泡数均出现降低,然而术后口服孕三烯酮FSH、LH水平及窦状卵泡数与术前和对照组比较,差异均没有统计学意义.E2水平与治疗前及治疗后组间比较,差异有统计学意义(P<0.05);2组不良反应发生率比较差异无统计学意义.结论 应用腹腔镜卵巢剥脱术联合孕三烯酮治疗卵巢囊肿的临床疗效疗效显著,不良反应小、安全可靠、性价比高.并且对卵巢功能有较大的改善,此方法具有临床研究价值.
Effect of laparoscopic ovarianectomy combined with gestrinone in the treatment of ovarian cysts and its effect on FSH, LH and E2
Objective To investigate the clinical effect of laparoscopic ovarian surgery combined with gestrinone in the treatment of ovarian cysts and its effect on FSH, LH and E2, for the clinical diagnosis and treatment to provide reference. Methods 60 cases of ovarian cysts from June 2014 to June 2016 in our hospital were selected and randomly divided into control group and treatment group with 30 cases in each group. The treatment group was treated with laparoscopic ovariectomy with gestrinone, two group of patients were treated for 6 months as a course of treatment. FSH, LH and E2 were detected by radioimmunoassay, the number of antral follicles was measured under transvaginal ultrasonography. Results The total effective rate of the treatment group (80%) was significantly higher than that of the control group (40%), the difference was statistically significant (P<0.05), the treatment group and control group after oral administration of gestrinone FSH, LH and E2 levels and the number of antral follicles decreased, however, after oral administration of gestrinone FSH, LH levels and the number of antral follicles were compared with those of the control group, the differences were not statistically significant,E2 levels were compared with those before and after treatment, the difference was statistically significant (P<0.05) There was no significant difference in the incidence of adverse reactions between the two groups. Conclusion Laparoscopic ovariectomy combined with gestrinone treatment of ovarian cysts has significant curative effect, little side effect, safe and reliable, and high cost performance. And the ovarian function has a greater improvement, this method has clinical research value.

laparoscopic ovarianectomygestrinoneovarian cystFSHLHE2

陈小娣、林慧敏

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台州市路桥区第三人民医院 妇产科,浙江 台州 318056

台州市中心医院 妇产科,浙江 台州 318000

腹腔镜卵巢剥脱术 孕三烯酮 卵巢囊肿 FSH LH E2

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(1)
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