目的 比较分析三子养亲汤和盐酸氨溴索治疗毛细支气管炎的临床效果.方法 收集125例毛细支气管炎患者的完整资料进行回顾性分析研究,随机数字表法分为对照组(62例)和观察组(63例),分别给予常规盐酸氨溴索治疗和三子养亲汤治疗.观察2组的临床症状改善情况,住院时间以及治疗效果,并对患者进行生活治疗评分和治疗安全性检测.结果 观察组的咳嗽、喘憋、气促、喉中痰鸣、啰音消失时间以及住院时间均显著短于对照组,差异有统计学意义(P<0.05).经疗效判定,观察组总有效率为95.24%,显著高于对照组的72.58%,差异有统计学意义(P<0.05).治疗后3个月利用生活质量综合评定问卷(generic quality of life inventory-74,GQOLI-74)对2组患者进行评分,观察组总分以及各项指标得分均显著高于对照组,差异有统计学意义(P<0.05).治疗前后分别对2组进行血常规以及肝肾功能、尿常规等指标检测,经检测和比较均未出现异常,且2组在治疗前后均未见任何不良反应出现.结论 对毛细支气管炎患者实施三子养亲汤治疗疗效确切,与常规盐酸氨溴索治疗进行比较可以更好的改善患者的临床症状和体征,缩短住院时间,提高治疗有效率以及患者的生活质量,且无不良反应的出现,是一种安全有效的治疗方法.
Comparison of clinical efficacy of Sanziyangqin decoction and ambroxol hydrochloride in treatment of bronchiolitis
Objective To compare and analysis of the clinical effect of Sanziyangqin decoction and ambroxol hydrochloride in the treatment of bronchiolitis.Methods 125 cases of bronchiolitis patients with complete data collected were retrospectively analyzed, randomly divided into control group ( 62 cases ) and observation group ( 63 cases ) , were treated with conventional ambroxol hydrochloride and Sanziyangqin decoction. The improvement of clinical symptoms, hospitalization time and treatment effect of the two groups were observed.Results The observation group of cough, wheezing, shortness of breath, throat phlegm and rales disappeared time and hospitalization time were significantly shorter than the control group, the difference was statistically significant (P<0.05).After treatment, the observation group of the total effective rate was 95.24%, significantly higher than the control group 72.58%, the difference was statistically significant (P<0.05).After Three months of treatment, the quality of life (GQOLI-74) was used to evaluate the scores of the patients in the two groups.The scores of the observation group were significantly higher than those of the control group, the difference was statistically significant (P<0.05).Before and after treatment in the two groups respectively were detected in blood and liver and kidney function, urine routine and other indicators, the detection and comparison were not abnormal, and the two groups before and after treatment were not found any adverse reaction.Conclusion The treatment of bronchiolitis in patients with Sanziyangqin decoction has the exact effect, compared with conventional ambroxol hydrochloride treatment can better improve the patient's clinical symptoms and signs, shorten the hospitalization time, improve the treatment efficiency and quality of life of patients, and there is no adverse reactions, is a safe and effective treatment method.