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乌司他丁对急腹症患者围术期多系统功能状态的影响

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目的 观察与研究乌司他丁对急腹症患者围术期多系统功能状态的影响状态.方法 选取2015年10月~2016年7月于丽水市人民医院进行手术治疗的60例急腹症患者为研究对象,将其随机分为对照组(常规围术期治疗组)30例和观察组(常规治疗加乌司他丁组)30例,检测比较2组患者术前及术后2、5 d及7 d的肝功能、肾功能、胃肠功能及免疫功能相关指标.结果 术前2组患者的肝功能、肾功能、胃肠功能及免疫功能相关指标比较差异无统计学意义;术后2、5及7 d,观察组的肝功能、肾功能、胃肠功能及免疫功能相关指标改善均显著优于对照组,差异均具有统计学意义(P<0.05).结论 乌司他丁可有效地保护急腹症患者围术期多系统的功能状态,在此类手术患者中的应用价值较高.
Effect of ulinastatin for multi system function state of patients with acute abdomen during the the perioperative period
Objective To observe and study the influence state of ulinastatin for multi system function state of patients with acute abdomen during the the perioperative period.Methods 60 patients with acute abdomen treated with operation in our hospital during the time of October 2015 to July 2016 were selected as the research object, and they were randomly divided into control group ( conventional perioperative treatment group ) 30 cases and observation group(conventional treatment and ulinastatin group)30 cases,then the liver function,renal function,gastrointestinal function and immune function related indexes of two groups before the operation and at second,fifth and seventh day after the operation were detected and compared.Results The liver function,renal function,gastrointestinal function and immune function related indexes of two groups before the operation were compared ,,while the liver function,renal function,gastrointestinal function and immune function related indexes of observation group at second,fifth and seventh day after the operation were all significantly better than those of control group(P<0.05),those detection results of two groups after the operation all had significant differences.Conclusion The ulinastatin can effectively protect multi system function state of patients with acute abdomen during the the perioperative period,so its application value in these surgical patients is higher.

ulinastatinacute abdomenperioperative periodmulti system function state

张继盛、王理富、叶小荣

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丽水市人民医院 急腹症创伤外科,浙江 丽水 323000

乌司他丁 急腹症 围术期 多系统功能状态

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(2)
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