中国生化药物杂志2017,Vol.37Issue(3) :15-19.DOI:10.3969/j.issn.1005-1678.2017.03.004

酵母β-葡聚糖的提取方法及其生物活性与应用研究进展

Research status of the extraction methods, biological activites and application of yeast β-glucan

于明秀 王凤山
中国生化药物杂志2017,Vol.37Issue(3) :15-19.DOI:10.3969/j.issn.1005-1678.2017.03.004

酵母β-葡聚糖的提取方法及其生物活性与应用研究进展

Research status of the extraction methods, biological activites and application of yeast β-glucan

于明秀 1王凤山1
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作者信息

  • 1. 山东大学药学院/生化与生物技术药物研究所,山东济南250012
  • 折叠

摘要

酵母β-葡聚糖的提取方法很多,主要有酸法、碱法、酸碱结合法、碱-酶法、自溶-酶-碱法、诱导自溶-碱法、微波辅助-碱-酶法、自溶超声波耦合法、酶法等.对β-葡聚糖的生物学活性亦有较多研究,包括免疫调节、抗肿瘤、抗氧化、抗辐射、降血脂、作为益生元调节肠道菌群等方面的活性.酵母β-葡聚糖在动物养殖业、食品工业、化妆品行业均有应用.本文通过查阅近年来国内外相关文献,对酵母β-葡聚糖的提取方法及β-葡聚糖的活性与应用研究进展进行了综述.通过综述发现,寻求高效、快捷、无污染的酵母β-葡聚糖提取方法是研究的热点,酵母β-葡聚糖作为一种良好的生物反应调节剂在未来的食品与化妆品行业中会有更多的应用.

Abstract

By searching and analizing the related literatures of recent years, the extraction methods, biological activites and application of yeastβ-glucan were reviewed.It is found that there are many kinds of extraction methods, including acid method, alkali method, acid-alkali method, alkali-enzymatic method, autolysis-enzyme-alkali method, induced autolysis-alkali method, microwave assisted alkali-enzyme method, autolysis-ultrasonic coupling method, enzymatic method, etc.There are lots of biological activity study report on yeast β-glucan, envolving the activities of immune, anti-tumor, anti-oxidant, anti-radiation, lowering blood lipid, and regulating intestinal flora as prebiotics, etc.Yeast β-glucan is widely used in animal breeding industry, food industry and cosmetics industry.From the review we can know that seeking efficient, fast, pollution-free yeastβ-glucan extraction methods is the hot research point, and it will have more applications in food and cosmetics industries as good biological response regulator in the future .

关键词

酵母β-1,3-葡聚糖/提取方法/生物活性/应用

Key words

yeast β-1/3-glucan/extraction method/biological activity/application

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出版年

2017
中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
被引量1
参考文献量13
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