抗肿瘤干细胞活性物质研究进展
Research progress on the chemicals with cancer stem cell growth inhibitory activity
李娇 1汤华 1庄春林 1孙鹏 1马福家 2张文1
作者信息
- 1. 第二军医大学药学院海洋药物研究中心/海洋生物医药研究所,上海200433
- 2. 解放军455医院药剂科,上海200052
- 折叠
摘要
肿瘤干细胞是肿瘤侵袭、转移、复发及耐药的关键因素,寻找新型抗肿瘤干细胞药用活性物质已经成为抗肿瘤药物研究的热点.本文对近来抗肿瘤干细胞活性物质研究进展进行了综述,以期为抗肿瘤活性物质研究提供参考.
Abstract
Cancer stem cells play a crucial role in tumors'invasion, metastasis, recurrence and drug resistance.Investigation on the chemicals with tumor stem cell growth inhibitory activity has been greatly highlighted in the field of anti-tumor drug discovery.This paper briefly reviews the recent progress of chemical investigations on substances with tumor stem cell growth inhibitory activity , aiming to give readers a reference on anti-tumor drug discovery.
关键词
肿瘤干细胞/生长抑制活性/活性物质Key words
cancer stem cells/growth inhibitory activity/bioactive chemicals引用本文复制引用
基金项目
国家自然科学基金(41576157)
上海市优秀学科带头人计划(15XD1504600)
出版年
2017
NETL
NSTL
维普
万方数据