首页|丹芪舒心胶囊治疗冠心病合并高胆固醇血症患者的效果观察

丹芪舒心胶囊治疗冠心病合并高胆固醇血症患者的效果观察

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目的 研究丹芪舒心胶囊在冠心病合并高胆固醇血症中的应用.方法 选择2016年2月~2016年10月浙江省金华市中心医院进行治疗的冠心病合并高胆固醇血症患者140例,按照治疗方法不同分为对照组和观察组,对照组给予瑞舒伐他汀治疗,观察组在对照组基础上给予丹芪舒心胶囊治疗,观察比较2组患者hs-CRP、Hcy、TNF-α、血脂血糖水平变化.结果 治疗后,2组患者的hs-CRP、Hcy、TNF-α水平均明显降低(P<0.05),且观察组hs-CRP、Hcy、TNF-α水平均明显低于对照组,差异具有统计学意义(P<0.05).与治疗前比较,2组患者TC、TG、LDL-C均明显降低,HDL-C水平明显升高,差异均具有统计学意义(P<0.05);观察组TC、TG、LDL-C水平均明显低于对照组,差异具有统计学意义(P<0.05);2组治疗前后FPG水平无显著变化.结论 丹芪舒心胶囊治疗冠心病合并高胆固醇血症患者,能有效降低患者的hs-CRP、Hcy水平,改善血脂水平,同时降低炎症因子水平.
Effect of Danqi Shuxin capsule in treating patients with coronary heart disease complicated with hypercholesterolemia
Objective To observe the effect of Danqi Shuxin Capsule on patients with coronary heart disease complicated with hypercholesterolemia.Methods 140 cases of patients patients with coronary heart disease complicated with hypercholesterolemia from February 2016 to October 2016 in our hospital were selected, according to different treatment divided into observation group and control group,the control group treated with Rosuvastatin Calcium,the observation group treated with Danqi Shuxin capsule on the basis of the control group , observation and compared the change of hs-CRP, Hcy, TNF-α, blood lipid, blood sugar levels between two groups.Results After treatment,the levels of hs-CRP,Hcy and TNF-αin the two groups were significantly decreased (P<0.05),and the levels of hs-CRP, Hcy and TNF-αin the observation group were significantly lower than those in the control group (P<0.05).Compared with before treatment, the levels of TC, TG and LDL-C in the two groups were significantly decreased, HDL-C levels were significantly increased,the difference was statistically significant (P<0.05); the levels of TC, TG and LDL-C in the observation group were significantly lower than those in the control group (P<0.05).There was no significant change in FPG levels before and after treatment. Conclusion Danqi Shuxin capsule can effectively reduce the hs-CRP and Hcy levels in CHD patients with hypercholesterolemia , improve blood lipid levels, while reduce the level of inflammatory factors.

Danqi Shuxin capsulecoronary atherosclerotic heart diseasehypercholesterolemia.hypersensitive C-reactive proteinhomocysteine

程键、胡宪清、傅慎文

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浙江省金华市中心医院心内科,浙江金华321000

丹芪舒心胶囊 冠心病 高胆固血症 高敏C反应蛋白 同型半胱氨酸

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(3)
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