首页|参麦注射液对乳腺癌患者术后感染及相关血清指标的影响

参麦注射液对乳腺癌患者术后感染及相关血清指标的影响

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目的 观察参麦注射液对乳腺癌患者术后感染及相关血清指标的影响,为本类患者术后感染的预防提供依据.方法选取进行手术治疗的90例乳腺癌患者为研究对象,将其随机分为对照组(常规术后治疗组)45例和观察组(常规治疗加参麦注射液组)45例,然后将2组患者的术后感染率、用药前和用药后不同时间的炎性指标与免疫指标进行比较.结果观察组的术后总感染发生率为1例(2.22%),与对照组的4例(8.89%)比较,差异无统计学意义,用药后1、3、7 d时的炎性指标即降钙素原(PCT)、肿瘤坏死因子α(TNF-α)、白细胞介素-6(IL-6)及高敏C反应蛋白(hs-CRP)均低于对照组,免疫指标CD3+、CD4+、CD8+及CD3+CD4+均优于对照组(均P<0.05).结论参麦注射液可有效降低乳腺癌患者的术后感染发生率,对于感染相关影响指标也有积极的改善作用.
Influence of Shenmai injection for the postoperative infection and related serum indexes of patients with breast cancer
Objective To observe the influence of Shenmai injection for the postoperative infection and related serum indexes of patients with breast cancer,in order to provide evidence for the prevention of patients'postoperative infection.Methods 90 patients with breast cancerwere selected as the study object,and all the patients were randomly divided into control group(conventional postoperative treatment group)45 cases and observation group (conventional treatment and Shenmai injection group)45 cases,then the postoperative infection rates,inflammatory indexes and immune indexes before the treatment and after the treatment at different time were compared .Results The total postoperative infection rate of observation group was one case (2.22%),and it had no obviously difference compared with four cases (8.89%) of control group,the inflammatory indexes including PCT, TNF-α, IL-6 and hs-CRP at first,third and seventh day after the treatment were all lower than those of control group ,the immune indexes including CD3 +、CD4 +、CD8 +及 CD3 +CD4 +were all better than those of control group ( all P<0.05 ) .Conclusion The Shenmai injection can effectively control the postoperative infection rate of patients with breast cancer,and it also plays active improvement role for the infection related indexes.

Shenmai injectionbreast cancerpostoperative infectioninfection related serum indexes

李鹏飞、王晓春、朱林波、张鹏斌、李吉

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宁波市北仑区人民医院普外科,浙江宁波315800

参麦注射液 乳腺癌 术后感染 感染相关血清指标

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(3)
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