首页|奥扎格雷钠联合桂哌齐特治疗动脉硬化性脑梗死的临床疗效及对患者血液流变学、血脂的影响

奥扎格雷钠联合桂哌齐特治疗动脉硬化性脑梗死的临床疗效及对患者血液流变学、血脂的影响

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目的 观察奥扎格雷钠联合桂哌齐特治疗动脉硬化性脑梗死患者的临床疗效及对血液流变学、血脂的影响.方法选取2015年1月~2016年1月诸暨市第四人民医院就诊的动脉硬化脑梗死患者112例,随机分为观察组与对照组,各56例.对照组患者给予桂哌齐特治疗,观察组患者在对照组基础上联合奥扎格雷治疗,比较2组患者的临床疗效及对血液流变学、血脂的影响.结果观察组患者的治疗总有效率显著高于对照组(P<0.05);与治疗前对比,治疗后2组患者的血液流变学参数及血脂水平显著改善(P<0.05);且观察组患者的血液流变学参数及血脂水平的改善程度显著优于对照组(P<0.05).结论采用奥扎格雷钠联合桂哌齐特治疗动脉硬化性脑梗死患者临床疗效显著,能够显著改善患者的血液流变学参数及血脂水平.
Clinical effect of ozagrel sodium combined with cinepazide in the treatment of atherosclerotic cerebral infarction and its effect on hemorheology and blood lipid
Objective To observe the clinical effect of sodium ozagrel combined with cinepazide treatment of cerebral arteriosclerosis , and the influence on hemorheology and blood lipid.Methods 112 cases of arteriosclerosis in patients with cerebral infarction were randomly selected from January 2015 to January 2016 in our hospital, and were randomly divided into observation group and control group ,56 cases in each group, the control group were treated with cinepazide treatment, patients in the observation group was combined with ozagrel sodium, clinical curative effect and blood rheology were compared between the two groups study, blood lipid.Results The observation group the total efficiency was significantly higher than the control group ( P<0.05 ) .After treatment, compared with before treatment, blood rheology parameters and blood lipid levels of two groups were significantly improved ( P<0.05 ) , and the patients in the observation group improved the hemorheological parameters and blood lipid level was significantly better than the control group ( P<0.05 ) .Conclusion Ozagrel sodium combined with cinepazide maleate in the treatment of cerebral arteriosclerosis process,can significantly improve the hemorheological parameters and blood lipids, and the clinical curative effect.

Ozagrel sodiumcinepazidecerebral infarctionhemorheologyblood lipid

张建江、傅婷霞、傅科锋

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诸暨市第四人民医院内科,浙江诸暨311835

奥扎格雷钠 桂哌齐特 动脉硬化性脑梗死 血液流变学 血脂水平

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.37(3)
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