心脏超声在左卡尼汀治疗围产期心肌病心力衰竭患者中的评估价值
Evaluation of cardiac ultrasonography in the evaluation of congestive heart failure in peripartum cardiomyopathy patients treated with L-carnitine
范梅花1
作者信息
- 1. 丽水市妇幼保健院超声科,浙江丽水323000
- 折叠
摘要
目的 探讨心脏超声在左卡尼汀治疗围产期心肌病心力衰竭患者中的评估价值.方法 选取围产期心肌病心力衰竭患者64例,随机分为2组,对照组予以常规治疗,研究组联合应用左卡尼汀治疗,治疗前后进行心脏超声诊断并对比各项指标变化情况.结果 心脏超声诊断结果方面,治疗前2组患者的左心室舒张末期内径、左心室射血分数以及心输出量无明显区别,治疗后研究组左心室舒张末期内径、左心室射血分数以及心输出量显著高于对照组(P<0.05);治疗前2组患者的左心室短轴缩短率、左心室收缩末期内径以及每搏输出量无明显区别,治疗后研究组左心室短轴缩短率及每搏输出量显著高于对照组(P<0.05),左心室收缩末期内径显著低于对照组(P<0.05);研究组患者的治疗有效率显著高于对照组,同时不良反应显著低于对照组(P<0.05).结论左卡尼汀治疗围产期心肌病心力衰竭患者的效果确切,应用心脏超声可以准确评估患者的治疗效果,从而为临床治疗提供指导.
Abstract
Objective To evaluate the value of echocardiography in the evaluation of congestive heart failure (PHC) in peripartum cardiomyopathy patients.Methods 64 patients with congestive heart failure were randomly divided into two groups.The control group were treated with routine therapy.The study group were treated with levocarnitine in combination with routine therapy.Echocardiography was performed before and after treatment, and the changes of each index were compared.Results There was no significant difference in left ventricular end diastolic diameter, left ventricular ejection fraction and cardiac output between the two groups before treatment.After treatment, the left ventricular end diastolic diameter, left ventricular ejection fraction and cardiac output in study group after treatment were higher than those in control group(P<0.05).There was no significant difference in left ventricular short axis shortening, left ventricular end-systolic diameter and stroke volume between the two groups before treatment, but the left ventricular short axis shortening and stroke volume in study group after treatment were higher than those in control group (P<0.05), the left ventricular end-systolic diameter was lower ethan that in control group ( P<0.05 ) .The treatment effect of the study group was significantly higher than that in control group (P<0.05).The adverse reactions was significantly lower than that in the control group (P<0.05).Conclusion L-carnitine is effective in the treatment of heart failure in peripartum cardiomyopathy patients.It can be used to evaluate the therapeutic effect of cardiac ultrasound in order to provide guidance for clinical treatment.
关键词
心脏超声/左卡尼汀/围产期心肌病/心力衰竭/评估Key words
cardiac ultrasound/L-carnitine/peripartum cardiomyopathy/heart failure/evaluation引用本文复制引用
基金项目
浙江省丽水市科学计划(2013JYZB33)
出版年
2017
NETL
NSTL
维普
万方数据