摘要
目的 探讨复方亚甲蓝液局部封闭联合葛根加术汤治疗肛门瘙痒症患者的临床疗效.方法 选取2015年6月～2016年6月于杭州市红十字会医院就诊的肛门瘙痒症患者88例,采用数字随机法分为观察组和对照组,每组44例,观察组患者给予复方亚甲蓝液局部封闭联合葛根加术汤治疗,对照组患者给予咪康唑乳膏治疗,比较2组患者的治疗效果.结果 观察组临床总有效率显著高于对照组(P<0.05);2组患者治疗前的肛门瘙痒、皮肤湿疹样变、皮肤苔藓样变、皮肤色素沉着症状积分比较差异无统计学意义;观察组患者治疗后的肛门瘙痒、皮肤湿疹样变、皮肤苔藓样变、皮肤色素沉着症状积分显著低于对照组(P<0.05);观察组患者瘙痒消失、皮损消失、睡眠改善时间显著短于对照组(P<0.05);观察组患者治疗后1、3、6个月复发率显著低于对照组( P <0.05);观察组患者瘙痒消失、皮损消失、睡眠改善时间显著短于对照组( P <0.05);观察组患者治疗后1、3、6个月复发率显著低于对照组( P <0.05).结论 复方亚甲蓝液局部封闭联合葛根加术汤治疗能够有效改善肛门瘙痒患者的临床症状,治疗效果良好,复发率较低.
Abstract
Objective To discuss the clinical efficacy of compound methylene blue liquid local closure combined with Gegen Jiazhu decoction in the treatment of anal pruritus.Methods 88 cases of anal pruritus patients from June 2015 to June 2016 in our hospital were randomly divided into observation group and control group,44 cases in each group,the observation group was treated with ompound methylene blue liquid local closure combined with Gegen Jiazhu decoction,patients in control group were treated with miconazole cream,the efficacy of the two groups were compared.Results The total effective rate of the observation group was significantly higher than that of the control group(P<0.05); There were no significant differences in anal eczema,skin eczema,skin licheniformis and skin pigmentation symptoms before treatment between two groups; After treatment,the anal eczema,skin eczema,skin licheniformis and skin pigmentation symptoms score of the observation group was significantly lower than the control group(P<0.05); patients in the observation group,skin itching disappeared disappeared and the improvement of sleep time was significantly shorter than the control group(P<0.05); After treatment one,three,six months,the recurrence rate of observation group was significantly lower than the control group(P<0.05).Conclusion The clinical efficacy of compound methylene blue liquid combined with Gegen Jiazhu decoction can effectively improve the clinical symptoms of patients with anal itching,the treatment effect is good,the recurrence rate is low.
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维普
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