目的 探讨宫外孕方剂、米非司酮与甲氨蝶呤对难治性输卵管妊娠的治疗效果.方法 选取2015年1月～2016年12月中国人民解放军第八十九医院收治的难治性输卵管妊娠患者100例,根据随机数字表法分为中西医组(宫外孕治疗方剂+米非司酮+甲氨蝶呤)、西医组(米非司酮与甲氨蝶呤),各50例,对比2种方法的治疗效果.结果 治疗后,2组患者的β-HCG水平、异位妊娠包块直径均显著降低,中西医组的β-HCG、异位妊娠包块直径在治疗7、10、14 d时刻均低于西医组,差异具有统计学意义(P<0.05);中西医组治疗成功率为92.00％,高于西医组的84.00％,但差异无统计学意义,2组保守治疗失败的患者均转开腹手术治疗.中西医组血β-HCG值完全恢复正常时间、异位妊娠包块消失时间均显著低于西医组,差异具有统计学意义( P <0.05).结论 宫外孕方剂联合米非司酮与甲氨蝶呤能显著降低难治性输卵管妊娠能患者β-HCG水平和异位妊娠包块直径,明显缩短治疗时间.
Ectopic pregnancy treatment prescription, mifepristone and methotrexate in the treatment of refractory tubal pregnancy mass size and serum-HCG value change analysis
Objective To investigate the therapeutic effect of ectopic pregnancy prescription,mifepristone and methotrexate in the treatment of refractory tubal pregnancy.Methods 100 cases of refractory tubal pregnancy from January 2015 to December 2016 in our hospital,according to randomly divided into Chinese and western medicine group(ectopic pregnancy treatment prescription+mifepristone+methotrexate)and western medicine group(mifepristone and methotrexate)50 cases,compared two methods of treatment effect.Results After treatment,the two groups of patients with β-HCG level,ectopic pregnancy mass diameter showed a significant decrease,beta-HCG,ectopic pregnancy mass of Chinese and western medicine group were lower than the diameter of the western medicine group in the treatment of 7,10,14 days,the difference was statistically significant(P<0.05); The success rate of Chinese and western medicine group was 92.00％,which was higher than that of western medicine group(84.00％),but the difference was not statistically significant,failure of conservative treatment of patients were transferred to open surgery.In Chinese and western medicine group,the β-HCG value of blood beta was completely recovered and the disappearance time of ectopic pregnancy was significantly lower than that of western medicine group,and the difference was statistically significant(P<0.05).Conclusion Ectopic pregnancy prescription combined with mifepristone and methotrexate in the treatment of refractory patients with tubal pregnancy can accelerate the β-HCG level,ectopic pregnancy mass diameter reduced,can significantly shorten the treatment time.
NETL
NSTL
万方数据
维普
