目的 分析益心巴迪然吉布亚颗粒联合艾司西酞普兰治疗躯体形式障碍患者的临床疗效.方法 选取2014年3月~2015年3月本院接诊的90例躯体形式障碍患者作为本次研究对象.按照随机数表法分为观察组和对照组,各45例.对照组采用艾司西酞普兰治疗,观察组在对照组基础上加用益心巴迪然吉布亚颗粒治疗.观察2组患者治疗前后症状自评量表(SCL-90)、汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)评分,健康状况调查问卷简表(SF-36PCS)、精神健康总评(MCS)评分,不良反应情况,治疗疗效.结果 治疗后,观察组SCL-90、HAMD、HAMA评分显著低于对照组[(2.40±0.53)分vs.(2.47±0.56)分、(7.32±1.08)分vs.(13.69±2.81)分、(4.82±1.21)分vs.(9.93±2.02)分](P<0.05);SF-36PCS、MCS评分显著高于对照组[(42.97±10.63)分vs.(37.86±9.80)分、(50.86±11.27)分vs.(48.38±11.02)分](P<0.05);总有效率为95.55%,显著高于对照组73.33%( P <0.05).结论 益心巴迪然吉布亚颗粒联合艾司西酞普兰治疗躯体形式障碍临床显著,能够有效的缓解患者的焦虑抑郁,同时改善可改善患者的躯体症状,可作为治疗首选方案.
Curative efficacy of Yixin Bardiranjibuya Keli in treatment of somatoform disorders
Objective To evaluate the clinical efficacy of Yixin Bardiranjibuya Keli combined with escitalopram in the treatment of somatoform disorders.Methods 90 patients with somatoform disorders from March 2014 to March 2015,were recruited in our hospital as the subjects of this study.According to the random number method,the observation group and the control group were divided into observation group(45 cases)and control group(45 cases).The control group was treated with escitalopram,and the observation group was treated with Yixin Bardiranjibuya Keli on the basis of the control group.(SCL-90),Hamilton Depression Rating Scale(HAMD),Hamilton Anxiety Scale(HAMA),Health Status Questionnaire(SF-36PCS),Mental Health Overall Evaluation(SF-36PCS)before and after treatment,MCS score,adverse reaction,and curative effect.Results After treatment,the scores of SCL-90,HAMD and HAMA in the observation group were significantly lower than those in the control group [(2.40±0.53)vs.(2.47±0.56),(7.32±1.08)vs.(13.69±2.81),(4.82±1.21)vs.(9.93±2.02)],respectively(P<0.05),and the scores of SF-36PCS and MCS were significantly higher than those of the control group(P<0.05).The total effective rate was 95.55(48.38±11.02)points(P<0.05),and the adverse reactions were significantly lower than those in the control group [8.88%(4/45)vs 24.44%(11/45)%,Significantly higher than the control group 73.33%(P<0.05).Conclusion Yixin Bardiranjibuya Keli combined with escitalopram for the treatment of somatosensory disorder is significant and effective in relieving anxiety and depression of the patients and improving the physical symptoms of the patients,which can be used as the first choice of treatment.