首页|参芪复肝颗粒治疗慢性丙型肝炎的临床评价及对患者白细胞与中性粒细胞计数的影响

参芪复肝颗粒治疗慢性丙型肝炎的临床评价及对患者白细胞与中性粒细胞计数的影响

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目的 评价参芪复肝颗粒治疗慢性丙型肝炎的临床评价及对患者白细胞与中性粒细胞计数的影响.方法 选择2014年10月~2016年9月宁波市大榭开发区医院治疗的慢性丙型肝炎患者135 例为研究对象,随机分为对照组67 例,观察组68 例,对照组患者给予利血生进行治疗,而观察组患者则使用参芪复肝颗粒进行治疗,随后检测并记录两组患者治疗前、治疗后2、4、8 周对白细胞及中性细胞计数的情况,同时分析2 组患者治疗前后对肝功能的恢复情况,并对其临床效果作出综合评价.结果 2 组患者治疗前后的白细胞计数和中性细胞计数比较,差异具有统计学意义( P <0.05).结论 参芪复肝颗粒治疗慢性丙型肝炎的临床效果显著,有效抑制外周白细胞计数和中细胞计数减少,安全性更高.
Clinical evaluation of Shenqi Fugan granule for chronic Hepatitis C and its effect on WBC and neutrophil count
Objective To study the clinical evaluation of Shenqi Fugan granule for chronic Hepatitis C and its effect on WBC and neutrophil count.Methods 135 patients with chronic hepatitis C from October 2014 to September 2016 were randomly divided into control group(n=68)and control group(n=68).The patients in control group were treated with reserpine.The patients in the observation group were treated with Shenqi Fugan Granule,and then the numbers of leukocytes and neutrophils were measured before and after treatment at 2,4 and 8 weeks after treatment.Meanwhile,the patients in both groups were treated before and after treatment.Liver function recovery,and to make a comprehensive evaluation of its clinical effect.Results There were significant differences between the two groups before and after treatment(P<0.05).The difference between the two groups was statistically significant(P<0.05),and the difference between the two groups was statistically significant(P<0.05).After treatment,the liver function(alanine aminotransferase(ALT),aspartate aminotransferase(AST),total bilirubin(TBIL))in the observation group was significantly better than that in the control group,and the total effective rate(91.18%)in the observation group was significantly greater than that in the control group Total effective rate(85.07%),the difference between the two groups was statistically significant(P<0.05).Conclusion The clinical effect of Shenqi Fugan Granule on chronic hepatitis C is significant,which can effectively inhibit the decrease of peripheral white blood cell count and middle cell count,and the safety is higher.

Shenqi Fugan Granulechronic hepatitis Cleukocyteneutrophil count

顾旦红、熊志刚、朱旭凤

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宁波市大榭开发区医院 检验科,浙江 宁波 315812

参芪复肝颗粒 慢性丙型肝炎 白细胞 中性粒细胞计数

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(4)
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