目的 评价参芪复肝颗粒治疗慢性丙型肝炎的临床评价及对患者白细胞与中性粒细胞计数的影响.方法 选择2014年10月～2016年9月宁波市大榭开发区医院治疗的慢性丙型肝炎患者135 例为研究对象,随机分为对照组67 例,观察组68 例,对照组患者给予利血生进行治疗,而观察组患者则使用参芪复肝颗粒进行治疗,随后检测并记录两组患者治疗前、治疗后2、4、8 周对白细胞及中性细胞计数的情况,同时分析2 组患者治疗前后对肝功能的恢复情况,并对其临床效果作出综合评价.结果 2 组患者治疗前后的白细胞计数和中性细胞计数比较,差异具有统计学意义( P <0.05),且组间和时间进行比较,差异具有统计学意义( P <0.05).治疗后,观察组患者的肝功能(谷丙转氨酶ALT、谷草转氨酶AST、总胆红素TBIL)恢复情况显著优于对照组,且观察组患者的总有效率(91.18％)明显大于对照组的总有效率(85.07％),2组比较差异具有统计学意义( P <0.05).结论 参芪复肝颗粒治疗慢性丙型肝炎的临床效果显著,有效抑制外周白细胞计数和中细胞计数减少,安全性更高.
Efficacy and safety of Tanreqing injection in the treatment of elder chronic senile obstructive pulmonary disease
Objective To evaluate the efficacy and safety of Tanreqing injection in the treatment of elder chronic senile obstructive pulmonary disease.Methods 78 cases of chronic senile obstructive pulmonary disease patients from August 2014 to May 2015 in our hospitol were selected and divided into control group and experiment group,with 39 cases in each group.The patients in the both groups were give regular treatment,patients in the control group were given theophylline sustained release tablets 0.2 g oral,two times a day;The experiment group were treated on base of the control group were given Tanreqing injection 20mL+5％intravenous glucose injection 500mL.The clinical efficacy,type B brain natriuretic peptide(BNP),calcitonin(PCT),forced vital capacity(FVC),forced expiratory volume in one second(FEV1),forced vital capacity(FVC)/expected value,and adverse reactions were compared between the two groups.Results The clinical efficacy in experiment group was 94.87％,which significant higher than that in control group(82.05％,P<0.05).The level of BNP serum PCT in two groups after treatment were significantly decreased,and the experiment group was significantly lower than the control group(P< 0.05);FEV1/expected,value FEV1/FVC levels were significantly increased and the experiment group was significantly higher than that of the control group(P< 0.05).The adverse drug reactions was not statistically different between the two groups.Conclusion Tanreqing injection in the treatment of elder chronic senile obstructive pulmonary disease with significant clinical efficacy,and with high safety.
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