首页|七叶洋地黄双苷滴眼液联合532激光对糖尿病视网膜病变患者的疗效

七叶洋地黄双苷滴眼液联合532激光对糖尿病视网膜病变患者的疗效

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目的 探讨七叶洋地黄双苷滴眼液联合532 激光对糖尿病视网膜病变患者的疗效.方法 选取2012年11月~2015年11月期间宁波市第四医院收治的糖尿病视网膜病变患者65 例(130 眼),按照随机数字表法分为观察组33 例与对照组32 例.对照组单纯采用532 激光治疗,观察组在对照组基础上结合七叶洋地黄双苷滴眼液治疗.2 组疗程均为1 个月.比较2 组治疗疗效,视力改善情况,视网膜出血、渗出、水肿吸收时间,治疗前后黄斑部视网膜厚度变化.结果 治疗后,观察组治疗总有效率(96.97%)高于对照组(75.00%),差异有统计学意义(P<.0.05);观察组视力提高明显高于对照组,而下降明显少于对照组,差异均有统计学意义 (P<.0.05);观察组视网膜出血、渗出、水肿吸收时间快于对照组,差异有统计学意义 (P<.0.05);2组黄斑部视网膜厚度下降,差异有统计学意义 (P<.0.05);观察组黄斑部视网膜厚度低于对照组,差异有统计学意义 (P<.0.05).结论 七叶洋地黄双苷滴眼液联合532激光对糖尿病视网膜病变患者疗效显著,且可降低黄斑部视网膜厚度,具有重要临床研究意义.
Effect of esculin and digitalis glycosides eye drops combined with 532 laser on diabetic retinopathy
Objective To investigate the effects of esculin and digitalisglycosides eye drops combined with 532 laser on the treatment of diabetic retinopathy.Methods 65 cases(130 eyes)with diabetic retinopathy in our hospital from November 2012 to November 2015 were selected and divided into observation group(33 cases)and control group(32 cases).The control group was treated with 532 laser treatment,and the observation group was combined with esculin and digitalisglycosides eye drops.Two groups of treatment were one months.Therapeutic effect of two groups were compared,improvement of visual acuity,retinal hemorrhage,exudation,edema absorption time,before and after macular retinal thickness changes.Results After treatment,the total efficiency of the observation group(96.97%)was higher than the control group(75.00%),the difference was statistically significant(P<0.05),the visual acuity of the observation group was significantly higher than that of the control group,and decreased significantly less than the control group,the difference was statistically significant(P<0.05),the retinal hemorrhage,exudation and edema were observed in the observation group faster than the control group,the difference was statistically significant(P<0.05),the macular retinal thickness decreased in the two groups after treatment,the difference was statistically significant(P<0.05),the retinal thickness of the macular area was lower in the observation group than in the control group,the difference was statistically significant(P<0.05).Conclusion Esculin and digitalisglycosides eye drops combined with 532 laser in the treatment of diabetic retinopathy has significant effect,and can reduce the macular retinal thickness,which has important clinical significance.

esculin and digitalisglycosides eye drops532 laserdiabetic retinopathycurative effect

黄玮英、喻相林、康宁宁

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宁波市第四医院 眼科,浙江 宁波 315700

七叶洋地黄双苷滴眼液 532激光 糖尿病视网膜病变 疗效

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(4)
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