复方大黄五倍子含漱液联合牙周基础治疗对慢性牙周炎患者炎症因子水平的影响
Effect of compound rhubarb gallnut gargle combined with periodontal basic therapy on inflammatory factors in chronic periodontitis
蒋玲玲 1赵燕 1诸森阳1
作者信息
- 1. 余姚市第二人民医院 口腔科,浙江 余姚 315400
- 折叠
摘要
目的 探讨复方大黄五倍子含漱液联合牙周基础治疗对慢性牙周炎患者炎症因子水平的影响.方法 选取2014年6月～2015年5月余姚市第二人民医院收治的慢性牙周炎患者76 例,根据抽签法分为2 组,给予牙周基础治疗的为对照组,复方大黄五倍子含漱液联合牙周基础治疗的为观察组,每组各38 例,检测2 组治疗后龈沟液炎症水平.结果 治疗后,2 组龈沟液肿瘤坏死因子-α(TNF-ɑ)、超敏C-反应蛋白(hs-CRP)以及3 种白细胞介素(IL-6、IL-1β和IL-8)水平均显著低于治疗前,且观察组各炎症因子水平均显著低于对照组,差异均有统计学意义 (P<.0.05).2组牙龈指数(GI)和龈沟出血指数(SBI)较治疗前均下降,且观察组GI和SBI均低于对照组,差异均有统计学意义 (P<.0.05).结论 在慢性牙周炎的治疗上,复方大黄五倍子含漱液联合牙周基础治疗方案效果明显,可显著降低炎症水平.
Abstract
Objective To investigate the compound rhubarb gallnut gargle combined periodontal treatment effect on inflammatory factors in patients with chronic periodontitis.Methods 76 patients with chronic periodontitis from June 2014 to May 2015 in our hospital were selected and randomly divided into two groups,given periodontal treatment as control group,compound rhubarb gallnut gargle combined periodontal treatment as observation group,38 cases in each group,two groups were detected after treatment of gingival crevicular fluid levels of inflammation.Results After treatment,the gingival crevicular fluid of tumor necrosis factor-α(alpha TNF-α),high sensitive C-reactive protein(hs-CRP)and interleukin three(IL-6,IL-1 beta and IL-8)of two groups were significantly lower than those before treatment,and the observation group of inflammatory cytokine levels were significantly lower than the control group,the difference was statistically significant(P<0.05).The gingival index(GI)and gingival bleeding index(SBI)of the two groups were were lower than those before treatment,and the GI and SBI in the observation group were lower than those in the control group,the difference was statistically significant(P<0.05).Conclusion In the treatment of chronic periodontitis,compound rhubarb gallnut gargle combined periodontal basic treatment effect,can significantly reduce the level of inflammation.
关键词
牙周炎/白细胞介素/超敏C-反应蛋白/复方大黄五倍子/肿瘤坏死因子-αKey words
periodontitis/interleukin/high sensitivity C-reactive protein/compound rhubarb gallnut/tumor necrosis factor-α引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据