首页|养血止痛丸联合双柏散外敷治疗小儿髋关节滑膜炎的临床疗效分析

养血止痛丸联合双柏散外敷治疗小儿髋关节滑膜炎的临床疗效分析

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目的 观察研究养血止痛丸联合双柏散外敷治疗小儿髋关节滑膜炎的临床效果及安全性.方法 选取绍兴第二医院2013年11月～2015年5月收治疗的确诊为髋关节滑膜炎的患儿共60 例,按随机数字表法分为观察组和对照组各30 例.观察组给予常规西药治疗,对照组给予养血止痛丸联合双柏散外敷治疗,随访并记录2 组患儿髋关节疼痛VAS 评分及血液学指标等情况.结果 ①治疗5 d 后观察组髋关节疼痛VAS 评分为(3.50 ±0.46)分,低于对照组(4.51 ±0.55)分( P< 0.05).②观察组治疗后CRP、TNF-α、IL-6、IL-1分别为(3.01±1.73 mg/L、15.58±5.46 pg/mL、74.9±19.4 pg/mL、22.57±4.01 ng/L),均低于对照组(5.69±2.05 mg/L、32.47±4.16 pg/mL、97.6±24.2 pg/mL、32.17±4.38 ng/L)( P< 0.05).③治疗后,观察组总有效率达93.3％,高于对照组66.7％( P< 0.05).结论 养血止痛丸联合双柏散外敷治疗小儿髋关节滑膜炎的临床治疗效果确切,值得临床进一步研究和应用.
Analysis on the clinical effect of Yangxue Zhitong pills combined with Shuangbaisan on the treatment of children with hip synovitis
To observe the clinical effect of Yangxue Zhitong pills combined with Shuangbaisan on the treatment of children with hip synovitis in.Methods 60 children with hip synovitis from November 2013 to May 2015 were randomly divided into the observation group and the control group,30 cases in each group.The observation group were given conventional treatment and the control group was given Yangxuezhitong pills combined with Shuangbaisan.Hip VAS and blood flow index in the two groups were followed-up and compared.Results (5 days after treatment,hip VAS in the observation group(3.50±0.46),was lower than that of the control group(4.51±0.55)(P<0.05).②CRP,TNF-α,IL-6,IL-1 level in the observation group were(3.01±1.73mg/L,15.58±5.46pg/mlL,74.9±19.4pg/mL,22.57±4.01ng/L),which were lower than those in the control group(5.69±2.05mg/L,32.47±4.16pg/mL,97.6±24.2pg/mL,32.17±4.38ng/L)(P<0.05).③After treatment,total effective rate in the observation group(93.3％)was higher than that in the control group 66.7％(P<0.05).Conclusion The clinical therapeutic effect of Yangxue Zhitong pill combined with Shuangbaisan on the treatment of children with hip synovitis is exact,which is worthy of further clinical research and application.

Yangxue Zhitong pillShuangbaisanhip synovitischildren

梅妍、赵小乐、金建荣

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绍兴第二医院 儿科,浙江 绍兴 312000

绍兴第二医院 小儿儿科,浙江 绍兴 312000

养血止痛丸 双柏散 髋关节滑膜炎 小儿

2017

10.3969/j.issn.1005-1678.2017.04.055

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN：1005-1678
年,卷(期)：2017.(4)
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