中国生化药物杂志2017,Issue(4) :223-225.DOI:10.3969/j.issn.1005-1678.2017.04.073

聚维酮碘外用联合抗真菌药物治疗真菌性角膜炎患者的效果观察

Effect of povidone iodine combined with antifungal drugs in the treatment of fungal keratitis

陈辉
中国生化药物杂志2017,Issue(4) :223-225.DOI:10.3969/j.issn.1005-1678.2017.04.073

聚维酮碘外用联合抗真菌药物治疗真菌性角膜炎患者的效果观察

Effect of povidone iodine combined with antifungal drugs in the treatment of fungal keratitis

陈辉1
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作者信息

  • 1. 慈溪市人民医院 眼科,浙江 慈溪 315300
  • 折叠

摘要

目的 探讨聚维酮碘外用联合抗真菌药物治疗真菌性角膜炎患者的的疗效.方法 选取2014年3月~2016年3月慈溪市人民医院收治的96例患有真菌性角膜炎疾病的患者,按照治疗方式的差异分为观察组和对照组,每组48例.对照组实施聚维酮碘外用进行治疗,观察组在对照组基础上给予抗真菌药物进行治疗,比较2组患者的临床疗效.结果 观察组治疗总有效率97.9%高于对照组的85.4%,差异有统计学意义(χ2=4.909,P0.05的占有率明显高于对照组,差异有统计学意义(χ2=6.042,P <0.05);2组不良反应发生率比较差异无统计意义.结论 聚维酮碘外用联合抗真菌药物治疗真菌性角膜炎患者效果显著,能有效提高患者的视力,具有较高应用价值.

Abstract

Objective To analyze the effect of combined use of povidone iodine and antifungal drugs in the treatment of fungal keratitis.Methods 96 cases of fungal keratitis patients suffering from the disease as the research object from March 2014 to March 2016 in our hospital,according to different treatment methods,they were divided into observation group and control group,48 cases in each group,control group received povidone iodine topical treatment,the observation group used povidone iodine and topical antifungal agents the treatment,the clinical efficacy of the two groups received.Results The total efficiency of the observation group was 97.9%higher than that of the control group 85.4%,the difference was statistically significant(χ2=4.909,P< 0.05);the visual acuity >0.05 share of the observation group was significantly higher than the control group,the difference was statistically significant(χ2=6.042,P< 0.05); There was no significant difference in the incidence of adverse reactions between the two groups.Conclusion The combined use of povidone iodine and antifungal drugs in the treatment of fungal keratitis can produce a very significant therapeutic effect,effectively improve the visual acuity of patients,and has high application value.

关键词

聚维酮碘外用/抗真菌药物/真菌性角膜炎/疗效

Key words

topical povidone iodine/antifungal drugs/fungal keratitis/curative effect

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出版年

2017
中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
被引量4
参考文献量12
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