中国生化药物杂志2017,Issue(4) :278-280.DOI:10.3969/j.issn.1005-1678.2017.04.092

酚妥拉明联合呋塞米对肺炎伴心力衰竭患儿EDV、ESV水平及心电图的影响

Phentolamine combined with furosemide on pneumonia complicated with heart failure in children with EDV, ESV levels and ECG effects

夏科君 单淑琴 赵蓓
中国生化药物杂志2017,Issue(4) :278-280.DOI:10.3969/j.issn.1005-1678.2017.04.092

酚妥拉明联合呋塞米对肺炎伴心力衰竭患儿EDV、ESV水平及心电图的影响

Phentolamine combined with furosemide on pneumonia complicated with heart failure in children with EDV, ESV levels and ECG effects

夏科君 1单淑琴 1赵蓓2
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作者信息

  • 1. 宁波市妇女儿童医院 儿科,浙江 宁波 315000
  • 2. 台州市第一人民医院 儿科,浙江 台州 318020
  • 折叠

摘要

目的 研究酚妥拉明联合呋塞米治疗肺炎伴心力衰竭患儿的临床疗效.方法 选取2015年10月~2016年12月间收治的肺炎合并心力衰竭患儿92 例,采用随机数字法将其分为对照组和观察组,各46 例.对照组患儿接受常规治疗干预,在此基础上,观察组患儿接受酚妥拉明联合呋塞米治疗.比较2 组患儿的治疗总有效率和症状体征消失时间,同时比较心脏功能及心电图改善效果.结果 观察组的治疗总有效率(93.48%)明显高于对照组(71.74%)(χ2 =7.57,P <0.05);观察组的肺部啰音消失时间、喘息消失时间、心力衰竭控制时间及住院时间均明显低于对照组( P <0.05);治疗后,观察组的ESV明显低于对照组( P <0.05),EDV明显高于对照组( P <0.05),心电图指标改善程度明显优于对照组( P <0.05).结论 酚妥拉明联合呋塞米治疗肺炎伴心力衰竭患儿的临床疗效明显,能有效改善心脏结构及功能,减少心电图异常发生,治疗安全性较高.

Abstract

Objective To study the clinical effect of phentolamine combined with furosemide therapy in children with pneumonia complicated with heart failure.Methods The subjects were 92 cases of children with pneumonia complicated with heart failure in our hospital from October 2015 to December 2016,randomly divided into control group and observation group,46 cases in each group.The control group was treated with on the basis of routine treatment,the observation group,patients received phentolamine combined with furosemide treatment.Compared two groups of the total efficiency and the symptoms disappear time,and compare the cardiac function and electrocardiogram improvement effect.Results The total efficiency of observation group(93.48%)was significantly higher than the control group(71.74%)(χ2=7.57,P<0.05); observation group of the pulmonary rales disappeared time,breath,heart failure control time and hospitalization time were significantly lower than the control group(P<0.05); after treatment,the observation group of the ESV was significantly lower than the control group(P<0.05),EDV was significantly higher than that of control group(P<0.05),electrocardiogram indicators improved significantly better than the control group(P<0.01).Conclusion The clinical curative effect of phentolamine combined with furosemide in treatment of children with pneumonia complicated with heart failure significantly,can effectively improve the cardiac structureAnd function,reduce the occurrence of abnormal ECG,high safety,worthy of clinical promotion

关键词

酚妥拉明/呋塞米/肺炎/心力衰竭/患儿/临床疗效

Key words

phentolamine furosemide/Sami/pneumonia/children/heart failure/clinical curative effect

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出版年

2017
中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
被引量9
参考文献量8
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