摘要
目的 探讨不同浓度的舒芬太尼联合地佐辛在剖宫产术后静脉自控镇痛的作用.方法 随机选取2013年1月～2015年12月浙江大学金华医院选择剖宫产的孕妇120 例,随机分为D1 组、D2 组和D3 组,每组40 例.其中D1 组给予地佐辛0.3 mg/kg +舒芬太尼1.0 μg/kg +托烷司琼10 mg,D2 组给予地佐辛0.3 mg/kg +舒芬太尼1.5 μg/kg +托烷司琼10 mg,D3 组给予地佐辛0.3 mg/kg +舒芬太尼2.0 μg/kg +托烷司琼10 mg.观察对比3 组患者术后1、4、8、12、24、48 h 补救镇痛用药例数、镇静程度评分、视觉模拟评分以及不良反应发生率.结果 与D2、D3 组相比,D1 组视觉模拟评分明显升高,且差异有统计学意义(P<.0.05);与D1、D2组相比,D3组不良反应的发生率升高明显,且差异有统计学意义 (P<.0.05);3组患者镇静程度评分比较差异无统计学意义.结论 相比于其它浓度的舒芬太尼联合地佐辛方案,地佐辛0.3 mg/kg+舒芬太尼1.5 μg/kg+托烷司琼10 mg在剖宫产术后静脉自控镇痛的作用效果良好,且不良反应发生率较低.
Abstract
Objective To explore the Analgesic effect of dezocine combining with different concentrations of sufentanil on patient-controlled intravenous analgesia in patients undergoing cesarean section.Methods 120 patients of cesarean section patients from January 2013 to December 2015 in our hospital were randomly and equally selected in to into group D1,group D2 and group D3,40 cases in each group.Patients in group D1 were given dezocine 0.3mg/kg+sufentanil 1.0μg/kg+tropisetron 10mg,patients in group D2 were given dezocine 0.3mg/kg+sufentanil 1.5μg/kg+tropisetron 10 mg,patients in group D3 were given dezocine 0.3mg/kg+sufentanil 2.0μg/kg+tropisetron 10mg.Visual analogue scale(VAS),ramsay sedation scale(RSS),the number of remedy analgesic medication and side effects were observed and recorded 1,4,8,12,24 and 48 hours after surgery.Results Compared with D2 and D3 group,visual analogue score of D1 group was significantly increased,and the difference were statistically significant(P<0.05).Compared with D1 and D2 group,the incidence of adverse reactions in group D3 was significantly higher than that in group D1 and group D2,and the difference was statistically significant(P<0.05).There was no statistically significant difference in sedation scores among the three groups.Conclusion Compared with other concentrations of sufentanil combined with dezocine,the effect of intravenous patient-controlled analgesia after cesarean section was good with dezocine 0.3mg/kg+sufentanil 1.5μg/kg+tropisetron 10 mg,and the incidence of adverse reactions is low.
NETL
NSTL
维普
万方数据