剖宫产产妇围手术期抗菌药物的合理用药研究
Study on perioperative use of antibiotics in cesarean section
潘群 1陈鱼 1徐红枫1
作者信息
- 1. 慈溪市妇幼保健院 产科,浙江 慈溪 315300
- 折叠
摘要
目的 探讨剖宫产产妇围手术期抗菌药物使用情况.方法 选取2015年12月～2016年12月慈溪市妇幼保健院收治的192 行剖宫产术的产妇进行研究,按照入院顺序进行分组,分为对照组(95 例)和观察组(97 例),均给予常规围手术期抗菌药物治疗.观察组实施科学用药干预,对照组不予以干预.统计2 组的术后白细胞计数水平和术后体温复常时间以及住院时间,统计术后感染类型和感染率,并统计2 组的治疗相关费用.结果 观察组的白细胞计数显著高于对照组,术后体温复常时间以及住院时间则显著短于对照组,差异均有统计学意义( P<.0.05);术后2组患者均出现一定的感染现象,包括尿路感染、切口感染、产褥感染以及宫腔感染等,2组总感染率比较差异无统计学意义;观察组的抗菌药物费用、总药费、住院费用均显著低于对照组,且患者抗菌药费占总药费比例也显著低于对照组,差异均有统计学意义( P<.0.05).结论 剖宫产产妇围手术期抗菌药物的使用过程中,通过实施科学干预可以获得理想的效果,促进临床用药的合理性与规范性,有效降低抗菌药物费用及住院费用等,促进患者的术后恢复,且不会增加术后感染的出现.
Abstract
Objective To analyze the use of antibiotics in perioperative period of cesarean section,and to summarize the experience of scientific intervention to promote rational drug use.Method 192 cesarean section included in the study were inpatients in December 2015 to December 2016 in our hospital,were grouped according to the order of admission,divided into control group(95 cases)and observation group(97 cases),were given routine perioperative antibiotic treatment.The observation group was treated with scientific medication intervention,and the control group was not intervened.The two groups of white blood cell count,postoperative body temperature and hospitalization time were counted,the infection types and infection rate were counted,and the treatment costs of the two groups were counted.Results The white blood cell count of the observation group was significantly higher than the control group,postoperative body temperature recovery time and hospitalization time was significantly shorter than the control group,the difference was significant(P<0.05); after two groups appeared infection phenomenon,including urinary tract infection,incision infection and puerperal infection as well as intrauterine infection,and two groups in different types of infection and the infection rate by comparison there was no statistically significant difference; statistical analysis and comparison of treatment related costs of the two groups of patients,to observe antibacterial drug group,the total cost of expenses and hospitalization costs were significantly lower than that of the control group,and patients with antimicrobial drugs accounted for the total proportion of drugs were significantly lower than the control group,the difference was statistically significant(P<0.05).Conclusion Cesarean section perioperative use of antibiotics in the process,through the implementation of scientific intervention can obtain ideal effect,promote rational and normative clinical medication,reduce hospitalization expenses and antimicrobial drug costs,promote the recovery of patients after surgery,and does not increase the infection after operation.
关键词
剖宫产/围手术期/抗菌药物/感染/费用Key words
Cesarean section/perioperative period/antibiotics/infection/cost引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据