中国生化药物杂志2017,Issue(4) :343-344.DOI:10.3969/j.issn.1005-1678.2017.04.113

奥美拉唑配合手术治疗腹部闭合性损伤小肠破裂的效果观察

Observation on the effect of Omeprazole combined with operation on treatment of rupture of small intestine in closed abdominal injury

刘纪炎 梁元晓 章慧
中国生化药物杂志2017,Issue(4) :343-344.DOI:10.3969/j.issn.1005-1678.2017.04.113

奥美拉唑配合手术治疗腹部闭合性损伤小肠破裂的效果观察

Observation on the effect of Omeprazole combined with operation on treatment of rupture of small intestine in closed abdominal injury

刘纪炎 1梁元晓 1章慧2
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作者信息

  • 1. 浙江省新昌县人民医院 肛肠外科,浙江 新昌 312500
  • 2. 浙江省新昌县人民医院 急诊外科,浙江 新昌 312500
  • 折叠

摘要

目的 探究应用奥美拉唑与手术联合治疗腹部闭合性损伤并发小肠破裂的疗效.方法 选择浙江省新昌县人民医院2014年6月~2015年12月收治的64 例腹部闭合性损伤小肠破裂患者,随机分为对照组和试验组,每组32 例.对照组采用手术治疗,试验组采用手术配合奥美拉唑治疗.对比2 组患者的总有效率、各项生活质量指标、肠鸣音恢复时间以及排气时间.结果 试验组临床总有效率(90.6%,29/32)显著高于对照组(75.0%,24/32),差异有统计学意义( P< 0.05).试验组各项生活指标评分均显著优于对照组,差异有统计学意义( P< 0.05).试验组肠鸣音恢复时间(15.3±2.6)h,短于对照组的(23.8±6.8)h;试验组排气时间(23.6±2.2)h,低于对照组的(32.3±4.6)h,组间对比差异有统计学意义( P< 0.05).结论 奥美拉唑与手术联合治疗腹部闭合性损伤并发小肠破裂,可显著提升治疗效果,改善术后各项指标.

Abstract

Objective To explore the the effect of Omeprazole combined with operation on treatment of rupture of small intestine in closed abdominal injury.Methods From June 2014 to December 2014,64 cases in Xinchang county people's hospitalwith rupture of small intestine in closed abdominal were divided into the treatment group and the control group,32 cases in each group.The control group were treat with surgery,the treatment group were given surgery combined with Omeprazole.The total effective rate,quality of life,the recovery time of bowel sound and the echaust time in the two groups were compared.Results The total effective rate(90.6%,29/32)in the treatment group was significantly higher than that in thecontrol group(75.0%,24/32),the difference is significant(P< 0.05).The life index in the treatment group is significantly better than that in the control group(P<0.05).The recovery time of bowel sound in the treatment group(15.3±2.6)h,is shorter than that in the control group(23.8±6.8)h; the exhaust time(23.6±2.2)h in the treatment group is lower than that in the control group(32.3±4.6)h,the differencesis statistically significant(P< 0.05).Conclusion It can significantly improve the effect and postoperative indexes which omeprazole combined with surgical treatment on the treatment of rupture of small intestine in closed abdominal injury,Itshould be widely promoted.

关键词

腹部闭合性损伤/小肠破裂/奥美拉唑/手术治疗

Key words

closed abdominal injury/the ruptureof small intestine/Omeprazole/surgical treatment

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出版年

2017
中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
被引量2
参考文献量5
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