摘要
目的 研究无痛胃镜麻醉中舒芬太尼复合丙泊酚的应用及效果.方法 纳入余姚市第四人民医院2014年4月~2016年6月行无痛胃镜治疗的患者94 例并根据随机数字表法分为2 组.麻醉组A 采用芬太尼复合丙泊酚进行麻醉,麻醉组B 采用舒芬太尼复合丙泊酚进行麻醉.比较2 组患者麻醉效果优良率;意识消失时间、睁眼时间、恢复定向力时间、丙泊酚用量;不同时间点患者平均动脉压、心率的差异;麻醉不良反应发生率.结果 麻醉组B 麻醉效果优良率显著比麻醉组A 高( P< 0.05);麻醉组B相较于麻醉组A意识消失时间、睁眼时间、恢复定向力时间更短,丙泊酚用量更少( P< 0.05);给药前2组平均动脉压、心率的差异无统计学意义;给药后和苏醒后麻醉组B相较于麻醉组A平均动脉压、心率波动更小( P< 0.05).麻醉组B麻醉不良反应发生率显著比麻醉组A低( P< 0.05).结论 无痛胃镜麻醉中舒芬太尼复合丙泊酚的应用及效果确切,可维持手术过程患者生命体征稳定,起效快,苏醒快,有利于减少丙泊酚用量,减少并发症的发生,值得推广.
Abstract
Objective To discuss the application and effect of sufentanil combined with propofol on painless gastroscopy anesthesia.Methods In the fourth people's hospital of Zhejiang in April 2014-June 2016,94 cases treated with painless gastroscopy I were randomly divided into two equal groups.Anesthesia group A were anaesthetized with fentanyl and propofol,sufentanil and propofol for anesthesia group B.The anesthetic effect,the time of consciousness disappearance,eye opening time,recovery time of orientation,the dosage of propofol in the two groups were compared.The mean arterial pressure,heart rate and adverse reaction rate in the two groups were compared.Results The anesthetic effect in the anesthesia groupB is significant better than that in the anesthesia group A(P<0.05).Compared with the anesthesia groupA,the time of consciousness disappearance,eye opening and orientation recovery is shorter in the anesthesia groupB(P<0.05),The difference of the mean arterial drug Pressure and heart rate is not significant in the two groups before medication.After medication and wake up,compared with the anesthesia group A,the mean arterial pressure,heart rate fluctuation is smaller,and the adverse reaction rate is lower in the anesthesia group B,(P<0.05).Conclusion It is effective which sufentanil combined with propofol used in anesthesia in painless gastroscopy,It can stable vital signs of patients during operation,,work quickly,restore consciousness rapidly,and contribute to reduce complications,and is worthy of promotion.