摘要
目的 研究消化性溃疡黏附血凝块给予内科药物干预对比内镜干预的临床疗效.方法 将确诊并收治的62 例消化性溃疡黏附血凝块患者根据随机数字表分为研究组和对照组,每组31 例.对照组单纯给予埃索美拉唑静脉滴注及后续口服治疗.研究组给予内镜下止血治疗并后续埃索美拉唑口服治疗.对比2 组疗效、治疗概况及治疗前后各研究评分变化情况.结果 研究组总有效率为90.32％,显著好于对照组的70.97％( P< 0.05).研究组再出血率及中转手术率显著低于对照组( P< 0.05),研究组止血时间、住院时间显著快于对照组( P< 0.05),研究组医疗费显著少于对照组( P< 0.05).2组治疗前Blatchford评分、Rockall评分、SF-36评分差异无统计学意义,2组治疗后这三项评分均比治疗前显著优化( P< 0.05),研究组其各评分优化幅度显著优于对照组 ( P< 0.05).结论 消化性溃疡黏附血凝块给予内镜治疗可极大提升疗效,降低再出血及中转手术风险,更有效改善急性上消化道出血症状体征,提升患者生活质量.
Abstract
Objective To study the clinical effect of drug intervention on the treatment of peptic ulcer with blood clots in the Department of internal medicine.Methods From 62 cases of peptic ulcer adherent blood clot were randomly divided into study group and control group according to the random number table,31 cases in each group,in each group.The control group was treated with esomeprazole infusion and subsequent oral treatment.The study group was given endoscopic hemostasis and subsequent oral esomeprazole treatment.Compare the two groups of curative effect,treatment profile and treatment before and after the study of the changes in the situation.Results The total effective rate of the study group was 90.32％,which was significantly better than that of the control group(P<0.05),which was significantly better than that of the control group 70.97％.Research group of rebleeding rate and transfer rate of surgery was significantly lower than that of control group(P<0.05),the study group,the time of hemostasis,the time of hospitalization significantly faster than that of the control group(P<0.05),study group medical expenses are significantly less than the control group(P<0.05).The two groups before treatment Blatchford score,Rockall score,SF-36 score no significant difference,after treatment in the two groups of the three scores were compared with those before treatment significantly optimized(P<0.05)study group the score optimization was significantly better than the control group(P<0.05).Conclusion Peptic ulcer adhesion blood clot give endoscopic therapy can greatly enhance the efficacy,reduce bleeding and transfer the risk of surgery,more effectively improve the acute upper digestive tract bleeding symptoms and signs,improve the life quality of the patients.
NETL
NSTL
维普
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