瑞格列奈联合香砂六君丸对糖尿病肾病患者的影响研究
Study on effect of repaglinide combined with Xiangsha Liujun pillon patients with diabetic nephropathy
杨勇 1王霄一 1冯跃华 1丁敏1
作者信息
- 1. 浙江省湖州市第一人民医院肾内科,浙江湖州313000
- 折叠
摘要
目的 探究瑞格列奈联合香砂六君丸对糖尿病肾病患者血清胱抑素C及C反应蛋白水平的影响.方法 选取确诊糖尿病肾病患者80例,随机分成2组,每组40例.对照组给予瑞格列奈治疗,观察组在对照组的基础上给予香砂六君丸治疗,治疗12周,检测治疗前后血糖(FBG)、糖化血红蛋白(HbA1C)、血清胱抑素C(CysC)、C反应蛋白(C-reactive protein,CRP)以及24h尿微量白蛋白(24hUAE)的变化.结果 与治疗前相比较,2组CysC、CRP以及24hUAE均降低(P<0.05);与对照组相比较,观察组CysC、CRP以及24hUAE均较低(P<0.05),临床疗效较高(P<0.05).结论 瑞格列奈联合香砂六君丸治疗糖尿病肾病是临床有效的方法,且能显著降低血清CysC、CRP水平.
Abstract
Objective To explore the ziggy joint amomum six columns nai jun pill in patients with diabetic nephropathy urinary inhibition c and serum c-reactive protein levels.MethodsSelect 80 patients with diagnosis of diabetic nephropathy, randomly divided into 2 groups, 40 cases in each group.Craig column nai treatment, control group given on the basis of the observation group in the control group given six jun pill treatment, treatment of 12 weeks, before and after treatment were detected blood glucose (FBG), glycosylated hemoglobin (HbA1C), urinary inhibition c (CysC) and serum c-reactive protein (CRP) and 24 h urinary microalbumin urine trace albumin (24 hUAE) changes.ResultsCompared with before treatment, 24 hUAECysC, CRP and 2 group were lower (P< 0.05);Compared with control group, 24 huae CysC, CRP and the observation group were lower (P< 0.05), the clinical curative effect is higher (P< 0.05), and high safety.ConclusionZiggy joint amomum six columns nai jun pill treatment of the diabetic nephropathy is a effective way, and can significantly reduce serum CysC, CRP levels.
关键词
糖尿病肾病/瑞格列奈/香砂六君丸/血清胱抑素C/C反应蛋白Key words
diabetic nephropathy/repaglinide/Sweet sand six jun pill/CysC/CRP引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据