中药末贴敷联合无创通气对慢性阻塞性肺病急性加重期患者呼吸衰竭的治疗研究
Study on treatment of respiratory failure in patients with acute exacerbation of slow-blocking lung disease by chinese herbal medicine combined with noninvasive ventilation
林文波 1吴冠仪1
作者信息
- 1. 金华市中医医院肺病科,浙江金华321000
- 折叠
摘要
目的 研究中药末贴敷联合无创通气对慢性阻塞性肺病(慢阻肺)急性加重期患者呼吸衰竭的疗效.方法 纳入金华市中医医院收治74例慢阻肺急性加重期病例为研究对象,按照治疗对策差异,分为实验组(n=37)与对照组(n=37),对照组采取无创通气法,实验组于其基础予以中药末敷贴法,比较2组治疗前后心率、血气分析指标、通气指标以及并发症情况.结果 治疗后,2组PaO2水平对比差异无统计学意义,实验组心率、PaCO2明显低于对照组,而pH值、SaO2明显大于对照组(P<0.05);实验组最高低水平压力支持(PS)、感染控制窗产生时间、最高PEEP以及机械通气时间均明显短于对照组(P<0.05),且并发症总发生率21.62%,明显低于对照组64.86%(P<0.05).结论 对慢阻肺急性加重期患者采取中药末贴敷联合无创通气治疗方案,可显著改善心率与血气分析指标,且优化无创通气效率,尽早控制肺部感染,缩短无创通气时间,降低无创通气所带来的副作用.
Abstract
Objective To study the curative effect of traditional chinese medicine combined with noninvasive ventilation on respiratory failure in patients with acute exacerbation of chronic obstructive pulmonary disease.MethodsThe patients were divided into experimental group (n=37) and control group (n=37).The experimental group was treated with traditional chinese medicine combined with noninvasive ventilation.The control group was treated with noninvasive ventilation method.The heart rate, blood gas analysis index, ventilation index and complication were compared between the two groups before and after treatment.ResultsAfter treatment, the levels of PaO2 in the two groups were not significantly different.The heart rate and PaCO2 of the experimental group were significantly lower than those of the control group, while the pH value and SaO2 were significantly higher than those in the control group (P< 0.05), and the total incidence of complications was 21.62%, which was significantly lower than that of the control group (64.86%, P<0.05).The time of infection control window, the highest PEEP and the time of mechanical ventilation were significantly shorter than those of the control group (P< 0.05).ConclusionThe treatment of patients with acute exacerbation of chronic obstructive pulmonary disease(COPD) combined with noninvasive ventilation therapy can significantly improve the heart rate and blood gas analysis indexes, and optimize the noninvasive ventilation efficiency, control lung infection as soon as possible, shorten the time of noninvasive ventilation and reduce the side effects that noninvasive ventilation brought about.
关键词
中药末贴敷/无创通气/慢性阻塞性肺疾病/急性加重期/呼吸衰竭Key words
chinese medicine at the end of paste/non-invasive ventilation/slow-stop lung/acute exacerbation/respiratory failure引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据