首页|小儿康颗粒联合妈咪爱治疗小儿秋季腹泻98例临床观察

小儿康颗粒联合妈咪爱治疗小儿秋季腹泻98例临床观察

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目的 观察小儿康颗粒联合妈咪爱治疗98例小儿秋季腹泻的临床疗效.方法 2015年1月~2015年12月浙江省衢州市人民医院收治的秋季腹泻患儿98例,按随机数字表法将其分为观察组和对照组各49例.对照组患儿给予妈咪爱治疗,观察组患儿给予小儿康颗粒联合妈咪爱治疗.记录并分析2组患儿治疗1周后相关体征消失时间,治疗前后血清因子变化和临床疗效.结果 ①观察组治疗后发热消退时间、呕吐停止时间和大便性状恢复时间分别为(18.24±2.13h、1.59±0.51d、3.67±0.51d),均显著短于对照组(27.05±3.09h、2.72±0.64d、5.69±0.86d),且差异均具有显著性(P<0.05).②观察组治疗后血清超敏C-反应蛋白(hs-CRP)和肿瘤坏死因子-ɑ(TNF-ɑ)水平分别为(4.58±0.61ng/L、8.14±0.79pg/mL),均低于对照组(8.13±0.75ng/L、11.49±1.87pg/mL),且差异均具有显著性(P<0.05).(观察组治疗后血清白细胞介素-1(IL-1)和白细胞介素-6(IL-6)水平分别为(27.49±3.16、9.73±1.25)pg/mL,均低于对照组(40.16±5.72、12.65±1.77)pg/mL,且差异均具有显著性(P<0.05);④观察组治疗一周后总有效率为91.84%,显著高于对照组73.47%,且差异具有显著性(P<0.05).结论 小儿康颗粒联合妈咪爱可有效降低患儿炎症水平,提高治疗效果,是一种有效的治疗方案.
The clinical efficacy of Xiaoerkang granule combined with MAMIAI to 98 children with autumn ped-iatric diarrhea
Objective To analysis The clinical efficacy of XiaoErKang granule combined with MAMIAI to 98 children with autumn ped-iatric diarrhea.Methods98 children with diarrhea from January 2015 to December 2015 were divided into 49 cases with treatment group and 49 cases with the control group.The control group received MAMIAI,and the treatment group received XiaoErKang granule combined with MAMIAI,following-up and recording related signs disappearing time,changes of serum factors and the clinical results.Results①The fever subsided, stop vomiting and stool recovery time of treatment group were (18.24±2.13h,1.59±0.51d,3.67±0.51d),shortter than the control group with (27.05±3.09h,2.72±0.64d,5.69±0.86d),and the differences were statistically significant (P<0.05).②The hs-CRP and TNF-ɑ levels of treatment group were (4.58±0.61ng/L,8.14±0.79pg/mL),lowwer than the control group with (8.13±0.75ng/L,11.49±1.87pg/mL),and the differences were statistically significant (P<0.05).③The IL-1 and IL-6 levels of treatment group were(27.49±3.16,9.73±1.25)pg/mL,lowwer than the control group with (40.16±5.72,12.65±1.77)pg/mL,and the differences were statistically significant (P<0.05).④The treatment effect of treatment group were 91.84%,better than the control group with 73.47%,and the differences were statistically significant (P<0.05).ConclusionThe effece of XiaoErKang granule joint MAMIAI to children with diarrhea can reduce levels of inflammation,and it is effective.

XiaoErKang granuleMAMIAIautumn ped-iatric diarrhea

胡泽富、徐玲、王思为

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浙江省衢州市人民医院药学部,浙江衢州324000

浙江省衢州市人民医院麻醉科,浙江衢州324000

小儿康颗粒 妈咪爱 小儿秋季腹泻

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(5)
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