首页|疏肝解郁汤加心理疏导治疗肝郁气滞型功能性消化不良的随机对照研究

疏肝解郁汤加心理疏导治疗肝郁气滞型功能性消化不良的随机对照研究

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目的 对照研究疏肝解郁汤加心理疏导治疗肝郁气滞型功能性消化不良的疗效.方法 选取2015年1月~2016年1月期间住院及门诊患者治疗的130例肝郁气滞型功能性消化不良患者,随机进行分组.对照组65例给予常规治疗,治疗组65例在对照组治疗的基础上,同期给予疏肝解郁汤和心理疏导治疗,连续治疗4周后,对比2组患者临床治疗疗效.结果 治疗组有效率为94%,对照组有效率为78%,2组比较差异有统计学意义(P<0.05);治疗后,2组评分均降低,且与治疗前有显著改善,差异有统计学意义(P<0.05),治疗组明显低于对照组,差异有统计学意义(P<0.05);治疗后,2组患者Hp感染、胆汁反流情况均有所改善,治疗组明显优于对照组,差异有统计学意义(P<0.05);治疗组Hp尿素酶转阴率为71%,对照组转阴率为40%,2组比较差异有统计学意义(P<0.05);治疗后,2组患者胃排空时间明显改善,与治疗前对比均具有统计学意义(P<0.05),与对照组相比,治疗组胃排空时间改善效果更明显,差异具有统计学意义(P<0.05);治疗后2组患者焦虑、抑郁情绪评分明显改善,治疗后与对照组相比,治疗组焦虑、抑郁情况改善显著,差异有统计学意义(P<0.05);2组均未发生明显不良反应,差异无统计学意义.结论 疏肝解郁汤加心理疏导治疗肝郁气滞型功能性消化不良疗效确切,为临床治疗功能性消化不良(肝郁气滞型)提供一条有效的途径,同时也为中医药防治功能性消化不良提供新的理论依据.
The randomized controlled trial of functional dyspepsia of stagnation of liver-qi type treated by liver-coursing depression-resolving decoction added psychological counseling
Objective To control study the treatment effect of functional dyspepsia of stagnation of liver-qi type treated by liver-coursing depression-resolving decoction added psychological counseling.Methods130 patients with functional dyspepsia of liver-qi stagnation type who were treated in the inpatients and outpatients in our hospital from January 2015 to January 2016 were selected, to randomLy grouping.The 65 cases of the control group was given the conventional therapy, and the another 65 cases of the treatment group was given liver-coursing depression-resolving decoction added psychological counseling at the the same term based on the control.After the continue treatment for 4 weeks, to compared the clinical curative effect of them.ResultsThe treatment effective rate of the treatment group was 94%, he treatment effective rate of the control group was 78%, there was statistical significance (P<0.05).To compared with the grade of traditional Chinese medicine symptom (distending pain in the stomach, satiation, belching, inhibited defecation) and discovered that the grades of them were lower after treatment, and there has the significant improvements that compared with that before the treatment, there was statistical significance (P<0.05), and the treatment group was significantly lower than the control group, there was statistical significance (P<0.05).The Hp Infection and the bile regurgitation of them after treatment was significantly improved, the treatment group was significantly better than the control group, there was statistical significance (P<0.05), the treatment group was significantly better than the control, there was statistical significance (P<0.05).To compared the 71% of the negative conversion ratio of Hp urease detection of the treatment group that was significantly greater than the 40% of the control group after detection, there was statistical significance (P<0.05).The gastric emptying time of them was significant improved after treatment, and compared with that before the treatment, there was statistical significance (P<0.05).For the gastric emptying time, to compared with the control group, the improvement effect of the treatment group was outstanding, there was statistical significance (P<0.05).After treatment, the grade of anxiety and depression was significantly decreased of them, and to compared with the control group after treatment, the grade of anxiety and depression of the treatment group was significantly improved, there was statistical significance (P<0.05).There was no obvious untoward effects of them, there was no statistical significance.ConclusionThat has an exact effect of functional dyspepsia of stagnation of liver-qi type treated by liver-coursing depression-resolving decoction added psychological counseling, to provide an effective way for the clinic treatment of the functional dyspepsia (stagnation of liver-qi type).Meanwhile, to provide the new theoretical foundation for the traditional chinese medicine therapy of functional dyspepsia.

liver-coursing depression-resolving decoctionpsychological counselingstagnation of liver-qi typefunctional dyspepsia

黄敏芳、张巧真

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宁波市康宁医院药剂科,浙江宁波315201

疏肝解郁汤 心理疏导 肝郁气滞型 功能性消化不良

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(5)
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