振源口服液联合阿替洛尔治疗心脏神经官能症的临床观察
Clinical effects of Zhenyuan oral liquid combined with atenolol in treatment of cardiac neurosis
林肖峰 1蔡林伟1
作者信息
- 1. 浙江省台州市第一人民医院心内科,浙江台州318020
- 折叠
摘要
目的 观察振源口服液联合阿替洛尔治疗心脏神经官能症的临床疗效.方法 将浙江省台州市第一人民医院心内科2014年1月~2016年11月期间收治的130例心脏神经官能症患者进行随机分组,各65例.对照组给予阿替洛尔治疗,观察组在此基础上加用振源口服液.对比2组疗效差异以及不良反应.结果 ①观察组的总有效率为93.85%,高于对照组76.92%(P<0.05).②治疗后,观察组主要症状得分和HAMA得分分别为(4.08±1.38、13.05±2.58)分,均低于对照组(6.15±1.56、17.20±2.97)分(均P<0.05).③治疗后,观察组心率变异指标SDNN、SDANN、rMSSD和PNN50水平分别为(116.9±7.3ms、111.0±6.7ms、41.59±3.68ms、13.02±1.14%),均高于对照组(99.5±6.2ms、95.3±5.4ms、35.92±3.59ms、10.89±1.09%)(均P<0.05).④治疗后,观察组T波异常和室性早搏比例分别为(7.69%、7.69%),均低于对照组(20.00%、16.92%)(均P<0.05).⑤观察组不良反应比例为7.69%,低于对照组10.77%,但组间差异无统计学意义.结论 振源口服液可提高心脏神经官能症治疗疗效,且用药安全.
Abstract
Objective To observe clinical effects Zhenyuan oral liquid combined with atenolol in treatment of cardiac neurosis.Methods130 patients with cardiac neurosis from department of cardiology from January 2014 to November 2016 were grouped two groups and each with 65 cases.The control group were treated with atenolol, and observa-tion group was treated another with Zhenyuan oral liquid.Clinical effects and adverse reac-tion of two groups were compared.Results①Effective rate of observation group was 93.85%,higher than control group 76.92%(P<0.05).②Main symptom score and HAMA score of observation group were(4.08±1.38,13.05±2.58)point,lower than that of control group(6.15±1.56,17.20±2.97)point(all P<0.05).③ SDNN,SDANN,rMSSD and PNN50 level of observation group were (116.9±7.3ms,111.0±6.7ms,41.59±3.68ms,13.02±1.14%),higher than that of control group(99.5±6.2ms,95.3±5.4ms,35.92±3.59ms,10.89±1.09%)(all P<0.05).④ Proportion of T wave anomaly and ventricular premature beat of observation group were(7.69%,7.69%),lower than that of control group (20.00%,16.92%)(all P<0.05).⑤Adverse reaction ratio of observation group was 7.69%,higher than that of control group 10.77%,but there was no significant difference between groups.ConclusionZhenyu-an oral liquid can improve effects of patients with cardiac neurosis and medication safety.
关键词
振源口服液/阿替洛尔/心脏神经官能症/临床疗效Key words
Zhenyuan oral liquid/atenolol/cardiac neurosis/clinical effects引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据