首页|防风通圣散联合氟哌噻吨美利曲辛片治疗肛门直肠神经症的临床研究

防风通圣散联合氟哌噻吨美利曲辛片治疗肛门直肠神经症的临床研究

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目的 观察防风通圣散联合氟哌噻吨美利曲辛片治疗肛门直肠神经症的临床疗效.方法 研究对象为鄞州钱湖医院肛肠科2014年4月~2016年6月期间收治的92例肛门直肠神经症患者,随机分为2组,各46例.对照组给予氟哌噻吨美利曲辛片治疗,观察组在此基础上加用防风通圣散.对比2组治疗效果.结果 ①观察组的总有效率为95.65%,高于对照组78.26%(P<0.05).②治疗后,观察组SAS和SDS评分均低于对照组(P<0.05).③治疗后,观察组肛门坠胀、肛门疼痛、便意频频和肛门异物感评分以及SF-36量表中8个维度得分均优于对照组(P<0.05).④服药期间,对照组出现8.70%的不良反应患者,略高于观察组4.35%,但差异无统计学意义.结论 在氟哌噻吨美利曲辛片治疗肛门直肠神经症基础上加用防风通圣散,可提高治疗效果,缓解患者焦虑程度,从而改善患者生活水平.
Clinical efficacy of Fangfengtongsheng powder combined with Flupentixol and Melitracen tablets in treatment of anorectal neurosis
Objective To analyse clinical efficacy of Fangfengtongsheng powder combined with Flupentixol and Melitracen tablets in treatment of anorectal neurosis.Methods92 patients with anorectal neurosis from April 2014 to June 2016 were grouped two groups randomly, each with 46 cases.Two groups were treated with Flupentixol and Melitracen tablets and observation group was treated another with Fangfengtongsheng powder.Clinical efficacy of two groups were compared.Results①Total effective rate of observation group was 95.65%,higher than that of control group 78.26% (P<0.05).②After treatment,SAS and SDS score of observation group were lower than that of control group(P<0.05).③After treatment, anal bulge, anal pain, frequent defecation, anal foreign body sensation score and 8 dimensions of SF-36 scale score of observation group were better than that of control group(P<0.05).④The control group had 8.70% adverse reactions, compared with observation group 4.35%, the difference was not statistically significant.ConclusionFangfengtongsheng powder can improve the therapeutic effect of anorectal neurosis on the basis of Flupentixol and Melitracen tablets, relieve the anxiety level and improve the living standard of patients.

fangfengtongsheng powderflupentixol and melitracen tabletsanorectal neurosisquality of life

李密云、余春辉

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浙江宁波鄞州钱湖医院外科,浙江宁波315100

浙江宁波鄞州第二医院药剂科,浙江宁波315100

防风通圣散 氟哌噻吨美利曲辛片 肛门直肠神经症 生活质量

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(5)
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