左西孟旦注射液治疗急性失代偿性心力衰竭患者的临床疗效

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中文摘要：目的探讨左西孟旦注射液治疗急性失代偿性心力衰竭的临床疗效.方法选取自2016年1月~2017年1月来湖州市第一人民医院急诊重症监护室治疗的急性失代偿性心力衰竭患者70例,将其随机分为2组,各35例,观察组患者给予左西孟旦治疗,对照组患者给予多巴酚丁胺治疗.在治疗前后对患者的全身状况、24h尿量、BNP、LVEF、SV情况进行检测和评估,观察2组患者的治疗情况.结果 2组患者在治疗后的各项相关指标均明显优于治疗前,差异具有统计学意义(P<0.05),观察组患者的全身症状评分、BNP显著低于对照组,而24h尿量、LVEF、SV则明显高于对照组,差异具有统计学意义(P<0.05);观察组不良反应发生率为4.4%,显著优于对照组(37.5%),差异具有统计学意义(P<0.05).结论左西孟旦注射液能够有效改善患者心力衰竭症状,且患者不良反应少,治疗效果良好.

外文标题：Clinical efficacy of levosimendan injection in the treatment of patients with acute decompensated heart failure

外文摘要：Objective To investigate the clinical efficacy of levosimendan injection in the treatment of patients with acute decompensated heart failure.Methods70 patients with acute decompensated heart failure patients were selected from January 2016 to January 2017 in huzhou first people's hospital.35 cases of patients in control group were treated with levosimendan injection, and the other 35 cases of patients in experimental group was treated with dobutamine.BNP, 24 hourly urine volume, LVEF and SV were detected and the systemic clinical conditions were assessed both before and after the treatment.ResultsAfter treatment, all indexes of two groups were better than before(P<0.05).The extent of improvement of systemic symptoms and relevant indicators such as BNP, 24 hourly urine, LVEF and SV in experimental group was larger than that in control group (P<0.05).Adverse reaction rate of experimental group was 16.7%, and adverse reaction rate of control group was 43.8%, the differences were statistically significant (P<0.05).ConclusionLevosimendan injection can relieve symptoms of patients with acute decompensated heart failure,and it has less adverse reactions.

外文关键词：

levosimendan injectionacute decompensated heart failuredobutamine

作者：

嵇朝晖、温晓红、戴竹泉、潘慧斌

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作者单位：

湖州市第一人民医院急诊重症监护室,浙江湖州313000

关键词：

左西孟旦注射液急性失代偿性心力衰竭多巴酚丁胺

出版年：

2017

DOI：