首页|舒芬太尼在儿童手术的术后镇痛效果及安全性

舒芬太尼在儿童手术的术后镇痛效果及安全性

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的 分析析舒芬太尼在儿童手术的术后镇痛效果及安全性.方法 选取西宁市第三人民医院儿科2013年7月~2015年1月收治的80例小儿手术患者作为研究对象,采用单双号法分为对照组和观察组,每组40例.对照组给予瑞芬太尼,观察组给予舒芬太尼,并记录患儿进入手术室后5min基础值、诱导后、气管插管后、插管后30min及拔管后5min各时点的平均动脉压(mean arterial pressure,MAP)和心率(heart rate,HR).同时记录术后5min、15min和30min的镇静评分.结果 观察组在术后T4、T5、T6各时段镇痛评分均明显高于对照组(P<0.05);观察组在T0、T1、T2、T3各时期MAP和HR与对照组比较,差异无统计学意义,但观察组T4时MAP明显高于对照组(P<0.05);而观察组在T4时HR明显低于对照组(P<0.05).结论 舒芬太尼应用于小儿手术镇痛效果明显,且安全性较高.
Application of sufentanil in pediatric surgery and postoperative analgesia
Objective To investigate the safety and efficacy of sufentanil in pediatric surgery.Methods80 cases of pediatric surgery were prospectively selected pediatric methods in The Third People's Hospital of Xining from July 2013 to January 2015 as the research object, the patients were divided into two groups, control group and observation group, 40 cases in each group.The control group received remifentanil,observation group were given sufentanil, mean arterial pressure(MAP)and heart rate(HR)30min and 5min at each time point after extubation and 5min based value children after entering the operation room after induction were compared.The sedation scores of 5min, 15min and 30min after tracheal intubationwere recorded..ResultsThe pain scores in the observation grouppostoperative T4, T5, T6 each time were significantly higher than the control group (P<0.05);MAP and HRin the observation group at T0, T1, T2, T3 had no significant differencecompared with control group, MAP during T4 in the observation group was significantly higher than the control group (P<0.05);and HR in the observation group in the period of T4 was significantly lower than the control group (P<0.05).ConclusionThe application of sufentanil in pediatric surgery is effective and safe.

sufentanilpediatric surgeryanalgesiasafety

姜勇、唐晓慧、侯得伟

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西宁市第三人民医院,青海西宁810005

舒芬太尼 儿童手术 镇痛 安全性

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(5)
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