盐酸米诺环素软膏与甲硝唑药膜治疗牙周脓肿的安全性与可行性
Safety and feasibility of Minocycline Hydrochloride Ointment and metronidazole membrane in the treatment of periodontal abscess
江荣彬 1刘学忠 1李涛1
作者信息
- 1. 宁夏第五人民医院大武口医院口腔科,宁夏石嘴山753000
- 折叠
摘要
目的 探讨盐酸米诺环素软膏与甲硝唑药膜治疗牙周脓肿的安全性与可行性.方法 选取宁夏第五人民医院大武口医院口腔科2014年5月~2016年5月收治的牙周脓肿患者80例,随机将患者分为盐酸米诺环素软膏组(40例)和甲硝唑药膜组(40例)2组,对2组患者的牙周袋探诊深度、牙龈出血指数、菌斑指数、附着丧失、临床疗效、不良反应发生情况及复发情况进行统计分析.结果 盐酸米诺环素软膏组患者的牙周袋探诊深度、牙龈出血指数、菌斑指数、附着丧失均显著低于甲硝唑药膜组(P<0.05),治疗的总有效率95.0%(38/40)显著高于甲硝唑药膜组77.5%(31/40)(P<0.05),复发率2.5%(1/40)显著低于甲硝唑药膜组15.0%(6/40)(P<0.05),但2组患者的不良反应发生率(盐酸米诺环素软膏组10.0%、甲硝唑药膜组7.5%)之间的差异无统计学意义.结论 盐酸米诺环素软膏较甲硝唑药膜治疗牙周脓肿具有更高的安全性与可行性,值得在临床推广.
Abstract
Objective To investigate the safety and feasibility of Minocycline Hydrochloride Ointment and metronidazole membrane in the treatment of periodontal abscess.Methods80 cases of patients with periodontal abscess in our hospital from May 2014 to May 2016 were selected, these patients were randomly divided into Minocycline Hydrochloride Ointment group (n=40) and metronidazole membrane group (n=40) two groups, the periodontal probing depth, gingival bleeding index, plaque index, attachment loss, clinical efficacy, the incidences of adverse reactions and recurrence of the two groups were statistically analyzed.ResultsThe periodontal probing depth, gingival bleeding index, plaque index, attachment loss of the Minocycline Hydrochloride Ointment group were significantly lower (P<0.05), the total treatment efficiency 95% (38/40) was significantly higher than the metronidazole membrane group 77.5% (31/40) (P<0.05), the recurrence rate 2.5% (1/40) was significantly lower than the metronidazole membrane group 15% (6/40) (P<0.05), but the difference of the incidences of adverse reactions 10% (4/40), 7.5% (3/40) between the two groups was not significant.ConclusionMinocycline Hydrochloride Ointment metronidazole membrane in the treatment of periodontal abscess has higher safety and feasibility than metronidazole membrane, so is worthy of promotion in the clinical.
关键词
盐酸米诺环素软膏/甲硝唑药膜/牙周脓肿/安全性/可行性Key words
minocycline hydrochloride ointment/metronidazole membrane/periodontal abscess/safety/feasibility引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据