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铝碳酸镁治疗胆汁反流性胃炎33例的临床效果

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目的 分析铝碳酸镁治疗胆汁反流性胃炎的临床疗效.方法 选取2013年5月~2014年5月来长治市第三人民医院就诊的胆汁反流性胃炎患者(n=66)作为本次研究对象,随机分为对照组和观察组,各33例.对照组给予硫糖铝治疗,每次4片,4次/d,观察组患者采用铝碳酸镁进行治疗,每次1~2片,3~4次/d,对比分析观察组与对照组患者的临床治疗效果.结果 经4周治疗后对照组总有效28例、总有效率84.85%,观察组33例患者的治疗总有效例数为32例,治疗总有效率为96.97%.观察组治疗总有效率高于对照组(P<0.05).治疗过程中,对照组发生腹泻2例、皮肤瘙痒3例,并发症发生总例数为5例,并发症发生率为15.15%;观察组患者中腹泻1例、消化不良2例,并发症发生总例数为3例,并发症发生率为9.09%.2组并发症发生率比较差异无统计学意义.结论 采用铝碳酸镁治疗胆汁反流性胃炎患者临床疗效显著,能够在一定程度上提高治疗有效率,安全性较高.
Clinical effect of hydrotalcite in treating bile reflux gastritis in 33 cases
Objective To evaluate the clinical effect of hydrotalcite in treatment of bile reflux gastritis.Methods66 patients with bile reflux gastritis were chosen in our hospital from May 2013 to May 2014 as the research object, according to the order of admission they were divided into two groups, 33 cases of control group were treated with sucralfate treatment, observation group patients were treated with hydrotalcite comparative analysis, clinical curative effect in the observation group and the control group of patients were compared.ResultsAfter treatment for a period of time after the 33 patients in the control group,the total effective treatment for 28 cases, the total effective rate was 84.85%, the observation group of 33 cases of patients treated with total effective number of 32 cases, the total effective rate was 96.97%.The effective rate of the observation group was significantly higher than that of the control group(P<0.05).After the corresponding treatment, the incidence of complication in the control group was 15.15%, the observation group was 9.09%.There was no significant difference in the incidence of complications between the two groups.ConclusionThe use of hydrotalcite in treatment of bile reflux gastritis clinical curative effect significantly, can improve the treatment efficiency to a certain extent, high safety.

bile reflux gastritishydrotalcitecurative effect

贾会兵、王世华、苗晓霞

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长治市第三人民医院消化科,山西长治046021

胆汁反流性胃炎 铝碳酸镁 疗效

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(5)
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