首页|抗生素联合外科手术及心理干预治疗先天性心脏病合并感染性心内膜炎的效果分析

抗生素联合外科手术及心理干预治疗先天性心脏病合并感染性心内膜炎的效果分析

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目的 探讨临床治疗先天性心脏病合并感染性心内膜炎的有效方案,分析在外科手术治疗基础上联合使用抗生素临床疗效,为临床治疗提供依据.方法 通过分析2009年1月~2016年12月宁波市第二医院收治的78例先天性心脏病合并感染性心内膜炎患者的临床资料,分为观察组和对照组各39例,对照组给予合适抗菌药物进行治疗,观察组患者术后根据标本培养和药敏试验选择合适的广谱抗生素进行治疗,治疗结束后观察2组临床疗效差异并进行总结分析.医护人员要根据患者心理情况给予心理疏导,为患者讲解疾病相关知识与相关治疗的重要性,及时消除/缓解患者的负面情绪,确保患者以良好的心态面对治疗.结果 78例先天性心脏病合并感染性心膜炎患者临床感染病菌主要为金黄色葡萄球菌和草绿色链球菌,此外还有少数患者感染粪肠球菌、表皮葡萄球菌、革兰氏阴性菌和混合菌.2组患者治疗结束后统计临床疗效结果显示观察组患者治愈率56.41%,临床有效率为97.43%,对照组患者治愈率35.90%,临床有效率为79.49%,组间差异具有统计学意义(P<0.05).术后统计2组患者生活质量评分,统计生活自理能力、心理感受、总体健康、药物依赖性和疼痛与不适5项指标,观察组患者疼痛与不适和总体健康2项指标显著优于对照组(P<0.05),其余指标组间差异无统计学意义.结论 临床给予先天性心脏病合并感染性心膜炎广谱抗生素联合外科手术治疗临床疗效可观,安全性可靠,患者术后恢复状况良好,可进行临床推广.
Effect of antibiotics combined with surgical treatment and psychological intervention on congenital heart disease complicated with infective endocarditis
Objective To investigate the clinical treatment of congenital heart disease complicated with infective endocarditis effective programs, joint analysis of the clinical efficacy of the use of antibiotics in surgery on the basis of providing a basis for clinical treatment.MethodsAnalysis of January 2009 to December 2016 in our hospital with congenital heart disease complicated with infective endocarditis clinical data of 78 cases of patients were randomly divided into observation group and control group of 39 cases, The control group was given appropriate antimicrobial treatment, patients in the observation group according to the samples of culture and drug sensitivity test choose appropriate broad-spectrum antibiotics for treatment, observation after treatment and the clinical efficacy of the two groups were analyzed.According to the medical staff were given psychological psychological counseling for patients to explain the importance of disease related knowledge and related treatment, timely eliminate / alleviate the negative emotion of patients with, to ensure that patients with a good attitude to face treatment.Results78 cases of congenital heart disease complicated with infective endocarditis clinical infection germs mainly Staphylococcus aureus and Streptococcus viridans, in addition to a small number of patients infected with Enterococcus faecalis, Staphylococcus epidermidis, gram-negative bacteria and mixed bacteria.Two groups of patients after treatment statistical clinical efficacy results show 56.41% cure rate in patients in the observation group, the effective rate was 97.43% clinical cure rate was 35.90% in the control group of patients, clinical effective rate was 79.49%, a statistically significant difference between groups (P<0.05).Statistical quality of life of patients after two scores, statistics of daily living, psychological feelings, general health, drug dependence and pain and discomfort five indicators, pain and discomfort, and two indicators of the overall health of patients in the observation group was significantly better than the control group (P<0.05), no significant difference.ConclusionThe clinical administration congenital heart infection endocarditis surgical treatment of broad-spectrum antibiotics combined with substantial clinical efficacy, safety, reliability, patients were recovering well, can be clinical.

congenital heart diseaseinfective endocarditissurgeryantibioticpsychological intervention

黄淑群、岑浩锋、孙优异

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宁波市第二医院心胸外科,浙江宁波315000

宁波市鄞州第二医院,浙江宁波315000

先天性心脏病 感染性心内膜炎 外科手术 抗生素 心理干预

2017

中国生化药物杂志
南京生物化学制药研究所,全国生化制药情报中心站,中国生化制药工业协会,中国药品生物制品检定所

中国生化药物杂志

ISSN:1005-1678
年,卷(期):2017.(5)
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