甘精胰岛素与诺和灵30R联合心理干预治疗2型糖尿病的临床效果比较
To compare the clinical effect of insulin glargine and Novolin 30R combined with mental intervention in the treatment of type 2 diabetes mellitus
马丹莉 1吴莲 1罗志芳1
作者信息
- 1. 嵊州市人民医院 内分泌科,浙江 嵊州 312400
- 折叠
摘要
目的 观察甘精胰岛素与诺和灵联合心理干预治疗2型治疗糖尿病的临床效果.方法 选取嵊州市人民医院内分泌科2015年6月~2016年10月收治的确诊为2型糖尿病的患者共68例,按随机数字表法分为甘精胰岛素组和诺和灵30R组,各34例,医护人员要根据患者心理情况给予心理疏导,为患者讲解疾病相关知识及治疗的重要性,及时消除/缓解患者的负面情绪,确保患者以良好的心态面对治疗;随访并记录2组患者1月时发生低血糖症比例、甘油三酯(TG)、血清总胆固醇(TC)、餐后2h血糖(2hPG)、糖化血红蛋白情况,采用统计学方法对数据进行分析.结果 ①治疗后甘精胰岛素组发生低血糖患者比例为2.94%,优于诺和灵组17.65%,且差异均有统计学意义(P<0.05).②治疗后甘精胰岛素组TG、TC指标分别为(1.70±0.21)mmol/L、(5.24±0.16)mmol/L,均优于诺和灵组(3.04±0.35)mmol/L、(5.58±0.22)mmol/L,且差异均有统计学意义(P<0.05).③治疗后甘精胰岛素组糖化血红蛋白为(7.02±0.18)%,低于诺和灵组(7.78±0.30)%,且差异均有统计学意义(P<0.05).结论 甘精胰岛素和诺和灵30R均可有效地控制血糖,甘精胰岛素低血糖事件发生率较低,治疗2型糖尿病的效果更好,值得临床进一步研究和应用.
Abstract
Objective To observe the clinical effect of treatment of type 2 diabetes with Glargine and Novolin 30R.Methods68 patients from June 2015 to October 2016,were randomly divided into insulin glargine group and Novolin 30R each group 34 cases, According to the medical staff were given psychological counseling for patients to explain the importance of disease related knowledge and related treatment, timely eliminate/alleviate the negative emotion of patients with, to ensure that patients with a good attitude to face treatment;Follow-up and It occurred in January when the two groups were recorded hypoglycemia ratio, triglyceride (TG), total cholesterol (TC), 2h postprandial blood glucose (2hPG), glycated hemoglobin, the use of statistical methods for data analysis.ResultsThe proportion of patients with insulin glargine group hypoglycemia after treatment 2.94%, better than Novolin group 17.65%, and the difference was significant (P<0.05).②After treatment glargine group TG, TC index were (1.70±0.21) mmol/L, (5.24±0.16) mmol/L, were better than Novolin group (3.04±0.35) mmol/L,(5.58±0.22) mmol/L, and the differences were statistically significant (P<0.05).After treatment glargine group glycated hemoglobin was (7.02±0.18)%, lower than Novolin group (7.78±0.30)%, and the differences were statistically significant (P<0.05).ConclusionGlargine and Novolin 30R can effectively control blood sugar, low insulin glargine hypoglycemia event rate, the better the treatment of type 2 diabetes, is worthy of further research and application.
关键词
甘精胰岛素/诺和灵30R/心理干预/2型糖尿病Key words
glargine/novolin 30R/psychological intervention/type 2 diabetes引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据