摘要
目的 观察三拗汤辨证加减联合阿奇霉素治疗小儿支原体肺炎临床效果.方法 选取宁波市北仑区中医院2013年8月~2014年8月76例小儿支原体肺炎患儿为研究对象,将患者抽签随机分为观察组与对照组,每组38例.对照组给予单纯阿奇霉素治疗,观察组在对照组的基础上给予三拗汤辨证加减治疗.比较2组临床疗效、退热时间、止咳时间、扁桃体充血消失时间、肺部啰音消失时间、住院时间及不良反应发生率.结果 观察组有效率94.37%高于对照组76.32%,差异有统计学意义(P<0.05).观察组退热时间(2.45±0.90)d、止咳时间(5.37±1.67)d、扁桃体充血消失时间(6.23±2.47)d、肺部啰音消失时间(7.18±1.58)d、住院时间(10.26±1.65)d均短于对照组,差异有统计学意义(P<0.05).2组不良反应发生率比较无统计学意义.结论 三拗汤辨证加减联合阿奇霉素治疗小儿支原体肺炎效果显著,可明显缩短患者症状、体征消失时间及住院时间,促进患儿迅速康复,安全性高,具有较好的临床应用价值.
Abstract
Objective To observe the clinical effect of Sangao Decoction combined with Azithromycin in the treatment of mycoplasmal pneumonia in children.MethodsFrom August 2013 to August 2014, 76 children with mycoplasma pneumonia were enrolled in this study.The patients were randomly divided into observation group and control group.The control group was treated with azithromycin alone, and the observation group was given the treatment of Sanao Decoction on the basis of the control group.Comparison of the two groups of clinical efficacy, fever time, cough time, tonsil disappearance time, lung rales disappear time, length of stay and the incidence of adverse reactions.ResultsThe effective rate was 94.37% in the observation group and 76.32% in the control group, which was statistically significant (P<0.05).(2.45±0.90) d, duration of coughing (5.37±1.67) d, duration of disappearance of tonsil (6.23±2.47) d, disappearance of rales (7.18±1.58) d, duration of hospital stay (10.26±1.65) d were shorter than the control group, which was statistically significant (P<0.05).The incidence of adverse reactions was not statistically significant.ConclusionThe effect of Sangao Decoction combined with azithromycin in the treatment of mycoplasma pneumonia in children can significantly shorten the symptoms and signs of the patients, the time of disappearance of the signs and the length of hospital stay, promote the rapid recovery of children, high safety, and have good clinical application value.